a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

235 compounds within 3 steps: 2 in 1, 25 in 2, 208 in 3

Three steps

2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulumOne of 2 routes
1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulumOne of 3 routes
2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulumOne of 3 routes
1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
16alpha,17alpha-dihydroxyprogesteroneReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. cytochrome P450 (17alpha-hydroxyprogesterone)
3. 17alpha-hydroxyprogesterone + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha,17alpha-dihydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by PIGL, CYP17A1endoplasmic reticulum
dodecanedioyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. Activation of dodecanedioic acid
Catalysed by PIGL, PIGWendoplasmic reticulum, cytosolOne of 4 routes
decanedioyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. Production of Sebacoylcarnitine
Catalysed by PIGL, PIGW, CPT1A, CPT1C and 1 moreendoplasmic reticulum, cytosolOne of 4 routes
octanedioyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. Production of Suberylcarnitine
Catalysed by PIGL, PIGW, CPT1A, CPT1C and 1 moreendoplasmic reticulum, cytosolOne of 4 routes
hexanedioyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. Activation of adipic acid for Formation of Adipoyl Carnitine
Catalysed by PIGL, PIGWendoplasmic reticulum, cytosolOne of 4 routes
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 7 routes
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 5 routes
2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-O-acyl-N-(acetyl)-sphing-4-enine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by PIGL, PIGW, CPT1A, CPT1C and 1 moreendoplasmic reticulum, cytosol
(13Z)-eicosenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 5 routes
4,8-dimethylnonanoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by PIGL, PIGW, CRAT, CROTendoplasmic reticulum, peroxisomeOne of 3 routes
tetradecanedioyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by PIGL, PIGW, ACAA1, HSD17B4 and 2 moreendoplasmic reticulum, peroxisome
hexadecanedioyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. Production of Hexadecanedioylcarnitine
Catalysed by PIGL, PIGW, CPT1A, CPT1C and 1 moreendoplasmic reticulum, cytosolOne of 2 routes
pristanoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. fatty-acid-CoA ligase
Catalysed by PIGL, PIGW, SLC27A2endoplasmic reticulum, cytosolOne of 2 routes
2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
undecanoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by PIGL, PIGW, ACSM4, ACSM1 and 4 moreendoplasmic reticulum, cytosolOne of 3 routes
1-octadecanoyl-sn-glycero-3-phosphoserineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phosphoserine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulum
1-O-acyl-N-(acetyl)-sphing-4-enineReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by PIGL, ASAH1, PLA2G15endoplasmic reticulumOne of 8 routes
(5Z)-tetradecenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 8 routes
(3E)-decenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by PIGL, PIGW, ACADM, ECHS1 and 2 moreendoplasmic reticulum, mitochondrial matrix
N-(acetyl)-sphing-4-enine-1-phosphateReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. N-(acetyl)-sphing-4-enine + ATP = N-(acetyl)-sphing-4-enine-1-phosphate + ADP + H(+)
Catalysed by PIGL, ASAH1, CERKendoplasmic reticulum
(2R,6)-dimethylheptanoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)
Catalysed by PIGL, PIGW, HADHA, ACAA2 and 1 moreendoplasmic reticulum, mitochondrial matrix
(7Z)-hexadecenoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 8 routes
tricosanoyl-CoAReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. phosphatidylinositol glycan anchor biosynthesis class W
3. long-chain-fatty-acid-CoA ligase (tricosanoic acid)
Catalysed by PIGL, PIGW, SLC27A2, ACSL4 and 6 moreendoplasmic reticulum, cytosolOne of 4 routes
2-(1-hydroxyethyl)thiamine diphosphateReach from here →
1. phosphatidylinositol glycan anchor biosynthesis class L
2. transport of acetate and pyruvate (cytosol to extracellular)
3. pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)
Catalysed by PIGL, SLC16A4, SLC16A5, SLC16A3 and 5 moreendoplasmic reticulum, extracellular space, cytosol, mitochondrial matrix