Pathway
Amino acid transport across the plasma membrane
Amino acid transport across plasma membranes is critical to the uptake of these molecules from the gut, to their reabsortion in the kidney proximal tubulues, and to their distribution to cells in which they are required for the synthesis of proteins and of amino acid derived small molecules such as neurotransmitters. Physiological studies have defined 18 "systems" that mediate amino acid transport, each characterized by its amino acid substrates, as well as its pH sensitivity and its association (or not) with ion transport. More recently, molecular cloning studies have allowed the identification of the plasma membrane transport proteins that mediate these reactions. Amino acid uptake mediated by 17 of these transporters is annotated here.
REACT:R-HSA-352230Reactome
What the reference databases state
Statements
31 statements
31 statements · 1 reference database · Subject: Amino acid transport across the plasma membrane · Sources: Reactome
- SLC16A10 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC1A4 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC1A5 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC25A29 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC36A1 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC36A2 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC36A4 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC38A1 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC38A2 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC38A3 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC38A4 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC38A5 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
Show the remaining 19
- SLC3A1 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC3A2 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC43A1 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC43A2 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC6A12 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC6A14 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC6A15 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC6A19 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC6A20 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC6A6 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC7A1 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC7A10 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC7A11 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC7A3 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC7A5 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC7A6 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC7A7 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC7A8 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only
- SLC7A9 participates in Amino acid transport across the plasma membraneProteinReactome R-HSA-352230Inferred only