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Proteins/UNIPROT:Q8N370
Uniporter that mediates the transport of the stereospecific L-phenylalanine, L-methionine and L-branched-chain amino acids, between the extracellular space and the cytoplasm and may control the transepithelial (re)absorption of neutral amino acid in kidney and small intestine. The transport activity is mediated through facilitated diffusion and is sodium ions-, chloride ions- and pH-independent Mediates the efflux of 3,3'-diiodo-L-thyronine (3,3'-T2) and 3-iodo-L-tyrosine (MIT)..
Function from UniProtKB (Q8N370), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 3 · transported by
3 compounds
3 compounds.
0 reported routes3 assembled routes
32 statements
32 statements · 7 reference databases · Subject: SLC43A2 · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea
12 reactions
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC36A1 or SLC43A1 or SLC43A2
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR05073CC BY 4.0Reference data
3 names
Resolves to: SLC43A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05080CC BY 4.0Reference data
L-phenylalanineL-phenylalanine
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC16A10 or SLC43A1 or SLC7A7 or SLC43A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05082CC BY 4.0Reference data
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC36A1 or SLC43A1 or SLC7A7 or SLC43A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05085CC BY 4.0Reference data
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC36A1 or SLC43A1 or SLC7A7 or SLC43A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05089CC BY 4.0Reference data
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC36A1 or SLC43A1 or SLC7A7 or SLC43A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05092CC BY 4.0Reference data
L-phenylalanineL-phenylalanine
Transported by SLC43A1 or SLC7A5 or SLC43A2 or SLC16A10 or SLCO3A1
Reaction pageReversibleBalanced
Rhea RHEA:27950CC BY 4.0Reference data
Transported by SLC43A1 or SLC7A5 or SLC43A2
Reaction pageDirection not assertedBalanced
Rhea RHEA:70939CC BY 4.0Reference data
Transported by SLC43A1 or SLC7A5 or SLC43A2
Reaction pageDirection not assertedBalanced
Rhea RHEA:70943CC BY 4.0Reference data
3,3'-diiodo-L-thyronine3,3'-diiodo-L-thyronine
Transported by SLC43A1 or SLC16A2 or SLC7A5 or SLC43A2 or SLC7A8
Reaction pageDirection not assertedBalanced
Rhea RHEA:71823CC BY 4.0Reference data
Transported by SLC38A8 or SLC43A1 or SLC7A5 or SLC43A2 or SLC38A9 or SLC25A44 or SLC38A10 or SLC7A8
Reaction pageRight to leftBalanced
Rhea RHEA:73011CC BY 4.0Reference data
3-iodo-L-tyrosine3-iodo-L-tyrosine
Transported by SLC43A1 or SLC16A2 or SLC7A5 or SLC43A2 or SLC7A8
Reaction pageDirection not assertedBalanced
Rhea RHEA:82883CC BY 4.0Reference data