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Proteins/UNIPROT:Q969I6
Symporter that cotransports neutral amino acids and sodium ions from the extracellular to the intracellular side of the cell membrane. The transport is electrogenic, pH dependent and partially tolerates substitution of Na(+) by Li(+). Preferentially transports smaller amino acids, such as glycine, L-alanine, L-serine, L-asparagine and L-threonine, followed by L-cysteine, L-histidine, L-proline and L-glutamine and L-methionine..
Function from UniProtKB (Q969I6), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 4 · transported by
4 compounds
4 compounds.
0 reported routes4 assembled routes
58 statements
58 statements · 4 reference databases · Subject: SLC38A4 · Sources: Bgee, Human-GEM, Reactome, Rhea
26 reactions
Transported by SLC7A2 or SLC38A4 or SLC7A1 or SLC7A3
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05068CC BY 4.0Reference data
Transported by SLC7A2 or SLC38A4 or SLC7A1 or SLC7A3
Reaction pageLeft to rightBalanced
8 names
Resolves to: SLC38A4
Human-GEM MAR05094CC BY 4.0Reference data
L-alanine+sodium(1+)L-alanine+sodium(1+)
Transported by SLC6A15 or SLC1A5 or SLC38A1 or SLC1A4 or SLC38A2 or SLC38A4 or SLC6A19
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05305CC BY 4.0Reference data
L-glutamine+sodium(1+)L-glutamine+sodium(1+)
Transported by SLC6A15 or SLC1A5 or SLC38A1 or SLC38A2 or SLC38A4 or SLC6A19
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05308CC BY 4.0Reference data
L-asparagine+sodium(1+)L-asparagine+sodium(1+)
Transported by SLC6A15 or SLC38A1 or SLC38A2 or SLC38A4
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05311CC BY 4.0Reference data
L-leucine+sodium(1+)L-leucine+sodium(1+)
Transported by SLC6A15 or SLC38A1 or SLC38A2 or SLC38A4 or SLC3A2 or SLC6A19
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05315CC BY 4.0Reference data
sodium(1+)+L-phenylalaninesodium(1+)+L-phenylalanine
Transported by SLC38A2 or SLC38A4 or SLC6A19
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05319CC BY 4.0Reference data
glycine+sodium(1+)glycine+sodium(1+)
Transported by SLC38A1 or SLC38A2 or SLC38A4 or SLC6A19
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05320CC BY 4.0Reference data
sodium(1+)+CHEBI:17203sodium(1+)+CHEBI:17203
Transported by SLC6A7 or SLC6A15 or SLC38A1 or SLC38A2 or SLC38A4 or SLC6A20
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05322CC BY 4.0Reference data
L-methionine+sodium(1+)L-methionine+sodium(1+)
Transported by SLC6A15 or SLC38A1 or SLC38A2 or SLC38A4 or SLC6A19 or SLC22A5
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05324CC BY 4.0Reference data
sodium(1+)+CHEBI:16857sodium(1+)+CHEBI:16857
Transported by SLC6A15 or SLC38A1 or SLC38A2 or SLC38A4
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05326CC BY 4.0Reference data
CHEBI:15971+sodium(1+)CHEBI:15971+sodium(1+)
Transported by SLC38A2 or SLC38A4
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05333CC BY 4.0Reference data