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Proteins/UNIPROT:Q8TF71
Sodium- and proton-independent thyroid hormones and aromatic acids transporter. Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels. Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa). Plays an important role in homeostasis of aromatic amino acids (By similarity)..
Function from UniProtKB (Q8TF71), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
18 statements
18 statements · 5 reference databases · Subject: SLC16A10 · Sources: Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
9 reactions
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC16A10 or SLC36A1 or SLC43A1 or SLC7A7
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05074CC BY 4.0Reference data
6 names
Resolves to: SLC16A10
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05080CC BY 4.0Reference data
L-phenylalanineL-phenylalanine
Transported by SLC3A2 & SLC7A8 or SLC7A5 or SLC16A10 or SLC43A1 or SLC7A7 or SLC43A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05082CC BY 4.0Reference data
Transported by SLC16A10
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR08081CC BY 4.0Reference data
L-phenylalanineL-phenylalanine
Transported by SLC43A1 or SLC7A5 or SLC43A2 or SLC16A10 or SLCO3A1
Reaction pageReversibleBalanced
Rhea RHEA:27950CC BY 4.0Reference data
Transported by SLC7A5 or SLC38A9 or SLC16A10 or SLCO3A1
Reaction pageReversibleBalanced
Rhea RHEA:68572CC BY 4.0Reference data
Transported by SLC7A5 or SLC36A4 or SLC16A10 or SLCO3A1
Reaction pageReversibleBalanced
Rhea RHEA:70947CC BY 4.0Reference data
3,3',5-triiodo-L-thyronine3,3',5-triiodo-L-thyronine
Transported by SLC16A2 or SLC7A5 or SLCO4C1 or SLC16A10 or SLCO4A1 or SLCO1C1 or SLC7A8 or SLC17A4
Reaction pageReversibleBalanced
Rhea RHEA:71811CC BY 4.0Reference data