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Proteins/UNIPROT:Q96QD8
Symporter that cotransports neutral amino acids and sodium ions from the extracellular to the intracellular side of the cell membrane. The transport is pH-sensitive, Li(+)-intolerant, electrogenic, driven by the Na(+) electrochemical gradient and cotransports of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier. May function in the transport of amino acids in the supply of maternal nutrients to the fetus through the placenta (By similarity). Maintains a key metabolic glutamine/glutamate balance underpinning retrograde signaling by dendritic release of the neurotransmitter glutamate (By similarity). Transports L-proline in differentiating osteoblasts for the efficient synthesis of proline-enriched proteins and provides proline essential for osteoblast differentiation and bone formation during bone development (By similarity)..
Function from UniProtKB (Q96QD8), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 4 · transported by
4 compounds
4 compounds.
0 reported routes4 assembled routes
344 statements
344 statements · 7 reference databases · Subject: SLC38A2 · Sources: Bgee, gene ontology, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways · Rows fetched: 300
26 reactions
L-alanine+sodium(1+)L-alanine+sodium(1+)
Transported by SLC6A15 or SLC1A5 or SLC38A1 or SLC1A4 or SLC38A2 or SLC38A4 or SLC6A19
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05305CC BY 4.0Reference data
10 names
Resolves to: SLC38A2
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05308CC BY 4.0Reference data
L-asparagine+sodium(1+)L-asparagine+sodium(1+)
Transported by SLC6A15 or SLC38A1 or SLC38A2 or SLC38A4
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05311CC BY 4.0Reference data
L-leucine+sodium(1+)L-leucine+sodium(1+)
Transported by SLC6A15 or SLC38A1 or SLC38A2 or SLC38A4 or SLC3A2 or SLC6A19
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05315CC BY 4.0Reference data
sodium(1+)+L-phenylalaninesodium(1+)+L-phenylalanine
Transported by SLC38A2 or SLC38A4 or SLC6A19
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05319CC BY 4.0Reference data
glycine+sodium(1+)glycine+sodium(1+)
Transported by SLC38A1 or SLC38A2 or SLC38A4 or SLC6A19
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05320CC BY 4.0Reference data
sodium(1+)+CHEBI:17203sodium(1+)+CHEBI:17203
Transported by SLC6A7 or SLC6A15 or SLC38A1 or SLC38A2 or SLC38A4 or SLC6A20
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05322CC BY 4.0Reference data
L-methionine+sodium(1+)L-methionine+sodium(1+)
Transported by SLC6A15 or SLC38A1 or SLC38A2 or SLC38A4 or SLC6A19 or SLC22A5
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05324CC BY 4.0Reference data
sodium(1+)+CHEBI:16857sodium(1+)+CHEBI:16857
Transported by SLC6A15 or SLC38A1 or SLC38A2 or SLC38A4
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05326CC BY 4.0Reference data
CHEBI:15971+sodium(1+)CHEBI:15971+sodium(1+)
Transported by SLC38A2 or SLC38A4
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05333CC BY 4.0Reference data
sodium(1+)+L-seryl residuesodium(1+)+L-seryl residue
Transported by SLC6A15 or SLC38A1 or SLC38A2 or SLC38A4 or SLC6A19
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR06375CC BY 4.0Reference data
proton+sodium(1+)+L-seryl residueproton+sodium(1+)+L-seryl residue
Transported by SLC38A5 or SLC38A1 or SLC38A2 or SLC38A4
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR06381CC BY 4.0Reference data