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a long-chain fatty acyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

12 compounds within 3 steps: 1 in 1, 2 in 2, 9 in 3

Does it reach a compound?

One step

a long-chain fatty acidReach from here →
1. a long-chain fatty acyl-CoA + H2O = a long-chain fatty acid + CoA + H(+)
Catalysed by ACOT7, ABCD3

Two steps

a 1-acylglycerone 3-phosphateReach from here →
1. a long-chain fatty acyl-CoA + H2O = a long-chain fatty acid + CoA + H(+)
2. 1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
Catalysed by ACOT7, ABCD3, AGPS
hexadecanoateReach from here →
1. a long-chain fatty acyl-CoA + H2O = a long-chain fatty acid + CoA + H(+)
2. 1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
Catalysed by ACOT7, ABCD3, AGPS

Three steps

hexadecanalReach from here →
Catalysed by ACOT7, ABCD3, AGPS, ALDH3B1 and 2 more
all-trans-retinyl hexadecanoateReach from here →

Catalysed by ACOT7, ABCD3, AGPS, RPE65

S-hexadecanoyl-N-acetylcysteamineReach from here →

a long-chain fatty acyl-CoA + H2O = a long-chain fatty acid + CoA + H(+)
1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
S-hexadecanoyl-N-acetylcysteamine + H2O = N-acetylcysteamine + hexadecanoate + H(+)

Catalysed by ACOT7, ABCD3, AGPS, PPT1 and 1 more

S-hexadecanoyl-N-acetylcysteine methyl esterReach from here →

a long-chain fatty acyl-CoA + H2O = a long-chain fatty acid + CoA + H(+)
1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
S-hexadecanoyl-N-acetylcysteine methyl ester + H2O = N-acetylcysteine methyl ester + hexadecanoate + H(+)

Catalysed by ACOT7, ABCD3, AGPS, PPT1

16-hydroxyhexadecanoateReach from here →

a long-chain fatty acyl-CoA + H2O = a long-chain fatty acid + CoA + H(+)
1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
hexadecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 16-hydroxyhexadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by ACOT7, ABCD3, AGPS, CYP4A11 and 2 more

hexadecanoyl-CoAReach from here →

a long-chain fatty acyl-CoA + H2O = a long-chain fatty acid + CoA + H(+)
1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate

Catalysed by ACOT7, ABCD3, AGPS, SLC27A2 and 10 more

N-hexadecanoylsphing-4-enineReach from here →

a long-chain fatty acyl-CoA + H2O = a long-chain fatty acid + CoA + H(+)
1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
N-hexadecanoylsphing-4-enine + H2O = sphing-4-enine + hexadecanoate

Catalysed by ACOT7, ABCD3, AGPS, NAAA and 3 more

a 1-O-alkylglycerone 3-phosphateReach from here →

a long-chain fatty acyl-CoA + H2O = a long-chain fatty acid + CoA + H(+)
1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)

Catalysed by ACOT7, ABCD3, AGPS

(R)-2-hydroxyhexadecanoateReach from here →

a long-chain fatty acyl-CoA + H2O = a long-chain fatty acid + CoA + H(+)
1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate
hexadecanoate + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (R)-2-hydroxyhexadecanoate + 2 Fe(III)-[cytochrome b5] + H2O

Catalysed by ACOT7, ABCD3, AGPS, FA2H