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Proteins/UNIPROT:Q96CQ1
Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Selectively transports cytosine, guanosine, inosine and uridine (deoxy)nucleoside mono-, di-, and triphosphates by antiport mechanism. Catalyzes uniport at much lower rate. May import (deoxy)nucleoside triphosphates in exchange for intramitochondrial (deoxy)nucleoside mono- and diphosphates, thus providing precursors necessary for de novo synthesis of mitochondrial DNA and RNA while exporting products of their catabolism. Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration..
Function from UniProtKB (Q96CQ1), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
122 statements
122 statements · 4 reference databases · Subject: SLC25A36 · Sources: Bgee, Hetionet, Human-GEM, Rhea
42 reactions
CHEBI:17239+CHEBI:17677CHEBI:17239+CHEBI:17677
Transported by SLC25A36
Reaction pageReversibleBalancedmitochondrial matrix, cytosol
Human-GEM MAR20132CC BY 4.0Reference data
cytidine 5'-monophosphate+CHEBI:17677cytidine 5'-monophosphate+CHEBI:17677
Transported by SLC25A36
Reaction pageReversibleBalancedmitochondrial matrix, cytosol
1 name
Resolves to: SLC25A36
CHEBI:17677+dCTPCHEBI:17677+dCTP
Transported by SLC25A36
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR20134CC BY 4.0Reference data
CHEBI:17677+dCDPCHEBI:17677+dCDP
Transported by SLC25A36
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR20135CC BY 4.0Reference data
CHEBI:17677+dCMPCHEBI:17677+dCMP
Transported by SLC25A36
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR20136CC BY 4.0Reference data
CHEBI:17677+GTPCHEBI:17677+GTP
Transported by SLC25A36
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR20137CC BY 4.0Reference data
CHEBI:17677+GDPCHEBI:17677+GDP
Transported by SLC25A36
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR20138CC BY 4.0Reference data
CHEBI:17677+GMPCHEBI:17677+GMP
Transported by SLC25A36
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR20139CC BY 4.0Reference data
CHEBI:17677+CHEBI:16497CHEBI:17677+CHEBI:16497
Transported by SLC25A36
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR20140CC BY 4.0Reference data
CHEBI:17677+CHEBI:28862CHEBI:17677+CHEBI:28862
Transported by SLC25A36
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR20141CC BY 4.0Reference data
CHEBI:17677+dGMPCHEBI:17677+dGMP
Transported by SLC25A36
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR20142CC BY 4.0Reference data
CHEBI:17677+CHEBI:16039CHEBI:17677+CHEBI:16039
Transported by SLC25A36
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR20143CC BY 4.0Reference data