all-cis-docosa-4,7,10,13,16,19-hexaenoic acid/Finding
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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Inhibits SYVN1
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Hypothesis“Mechanistically, DHA inhibited the ubiquitination of NRF1 via the cytoplasmic E3 ligases FBW7 and HRD1 at the ER membrane, thereby preventing its degradation.”
Quoted verbatim from NRF1 is upregulated by docosahexaenoic acid to ameliorate MASH through the inhibition of ER stress.. - Study
- mechanistic · not in humans
- Population
- not stated in the abstract
NRF1 is upregulated by docosahexaenoic acid to ameliorate MASH through the inhibition of ER stress.2026PMID:41545342Permalink
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To cite this finding: https://catalystproject.ai/e/01M2T9G65SC9PRKF6KE48D67XZ