Compound
14-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate
A polyunsaturated fatty acid anion that is the conjugate base of 14-HPDHE, obtained by deprotonation of the carboxy group; major species at pH 7.3.
Definition from ChEBI (CHEBI:83336), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C22H31O4
- Mass
- 359.486 g/mol
- Charge
- -1
- InChIKey
- OAGAUECBCOAGOL-BGKMTWLOSA-M
- SMILES
- CC/C=CC/C=CCC(/C=C/C=CC/C=CC/C=CCCC(=O)[O-])OO
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
- ALOX12BProteinUNIPROT:O75342substrate ofInferred only8 paths8 endpoints
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acidCompoundCHEBI:28125converted toInferred only3 paths3 endpoints
What the reference databases state
Statements
3 statements
3 statements · 1 reference database · Subject: 14-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate · Sources: Rhea
- 14-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate is converted to all-cis-docosa-4,7,10,13,16,19-hexaenoic acidCompoundRhea RHEA:43472Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is converted to 14-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoateCompoundRhea RHEA:43472Inferred only
- 14-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate is a substrate of ALOX12BProteinRhea RHEA:43472Inferred only
Reactions
1 reaction
all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+dioxygen14-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate
Catalysed by ALOX12B
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:43472CC BY 4.0Reference data
Other names
7 names
Resolves to: 14-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate
- Also called
- (4Z,7Z,10Z,12E,16Z,19Z)-14-hydroperoxydocosahexaenoate(1-)(4Z,7Z,10Z,12E,16Z,19Z)-14-hydroperoxydocosahexaenoate(1−)14-HPD(4,7,10,12,16,19)HE(1-)14-HPD(4,7,10,12,16,19)HE(1−)14-HpDHE14Hp-(4Z,7Z,10Z,12E,16Z,19Z)-DHE
- Systematic name
- (4Z,7Z,10Z,12E,16Z,19Z)-14-hydroperoxydocosa-4,7,10,12,16,19-hexaenoate