Compound

L-homoserine

Zwitterionic form of L-homoserine.

Definition from ChEBI (CHEBI:57476), read 2026-09-23. CC BY 4.0.

CHEBI:57476ChEBI

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Structure

2D depiction · 3D model shown

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A generated conformer of L-homoserine — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound
Formula: C4H9NO3
Mass: 119.12 g/mol
Charge: 0
InChIKey: UKAUYVFTDYCKQA-VKHMYHEASA-N
SMILES: [NH3+][C@@H](CCO)C(=O)[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

1 entity

1 entities reached.

0 reported hops1 assembled from the scaffold

CTHProteinUNIPROT:P32929substrate ofInferred only21 paths21 endpoints

What the reference databases state

Statements

2 statements

2 statements · 1 reference database · Subject: L-homoserine · Sources: Rhea

Order

L-homoserine is converted to 2-oxobutanoateCompoundRhea RHEA:24923Inferred only
L-homoserine is a substrate of CTHProteinRhea RHEA:24923Inferred only

Reactions

12 reactions

L-homoserine+acetyl-CoACHEBI:57716+coenzyme A(4-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:13701CC BY 4.0Reference data
L-homoserine+ATP(4-)CHEBI:57590+ADP(3-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:13985CC BY 4.0Reference data
L-homoserine+NAD(1-)CHEBI:537519+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:15757CC BY 4.0Reference data
L-homoserine+NADP(3-)CHEBI:537519+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:15761CC BY 4.0Reference data
L-homoserine+succinyl-CoACHEBI:57661+coenzyme A(4-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:22008CC BY 4.0Reference data
L-homoserineCHEBI:48306+water
Reaction pageDirection not assertedBalanced
Rhea RHEA:24919CC BY 4.0Reference data
L-homoserine2-oxobutanoate+ammonium
Catalysed by CTH
Reaction pageLeft to rightBalanced
Rhea RHEA:24923CC BY 4.0Reference data
L-homoserine+hydronL-homoserine+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:29003CC BY 4.0Reference data
L-homoserineCHEBI:143081
Reaction pageDirection not assertedBalanced
Rhea RHEA:59404CC BY 4.0Reference data
CHEBI:193130+waterCHEBI:78442+L-homoserine+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:74255CC BY 4.0Reference data
CHEBI:193130+waterCHEBI:78442+L-homoserine+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:74259CC BY 4.0Reference data
CHEBI:78902+waterCHEBI:194307+L-homoserine
Reaction pageDirection not assertedBalanced
Rhea RHEA:75379CC BY 4.0Reference data

Other names

2 names

Resolves to: L-homoserine

Also called: (2S)-2-ammonio-4-hydroxybutanoate
Systematic name: (2S)-2-azaniumyl-4-hydroxybutanoate