Compound
D-leucine
A D-α-amino acid zwitterion arising from the transfer of a proton from the carboxy to the amino group of D-leucine; major species at pH 7.3.
Definition from ChEBI (CHEBI:143079), read 2026-09-23. CC BY 4.0.
Structure
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- Class
- Organic compound
- Formula
- C6H13NO2
- Mass
- 131.175 g/mol
- Charge
- 0
- InChIKey
- ROHFNLRQFUQHCH-RXMQYKEDSA-N
- SMILES
- CC(C)C[C@@H]([NH3+])C(=O)[O-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
0 reported hops3 assembled from the scaffold
- SLC43A1ProteinUNIPROT:O75387transported byInferred only33 paths33 endpoints
- DAOProteinUNIPROT:P14920substrate ofInferred only11 paths11 endpoints
- L-leucineCompoundCHEBI:15603converted toInferred only3 paths2 endpoints
What the reference databases state
Statements
5 statements
5 statements · 1 reference database · Subject: D-leucine · Sources: Rhea
- D-leucine is converted to 4-methyl-2-oxopentanoateCompoundRhea RHEA:78211Inferred only
- D-leucine is converted to L-leucineCompoundRhea RHEA:59396Inferred only
- L-leucine is converted to D-leucineCompoundRhea RHEA:59396Inferred only
- D-leucine is a substrate of DAOProteinRhea RHEA:78211Inferred only
- D-leucine is transported by SLC43A1ProteinRhea RHEA:73015Inferred only
Reactions
5 reactions
Reaction pageDirection not assertedBalanced
Rhea RHEA:59396CC BY 4.0Reference data
CHEBI:58645+D-leucine+D-alanine+L-proline+2L-leucine+ACHEBI:191392+AH2+6water
Reaction pageDirection not assertedBalanced
Rhea RHEA:72047CC BY 4.0Reference data
Transported by SLC43A1
Reaction pageDirection not assertedBalanced
Rhea RHEA:73015CC BY 4.0Reference data
D-leucine+chloride+2sodium(1+)D-leucine+chloride+2sodium(1+)
Reaction pageDirection not assertedBalanced
Rhea RHEA:75323CC BY 4.0Reference data
D-leucine+dioxygen+water4-methyl-2-oxopentanoate+hydrogen peroxide+ammonium
Catalysed by DAO
Reaction pageLeft to rightBalanced
Rhea RHEA:78211CC BY 4.0Reference data
Where it reaches
10 systems, 20 regions, 33 tissues, 33 transporter routes — routes, not measurements: transporters known to carry D-leucine are expressed there, and no source reports it arriving.
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Other names
2 names
Resolves to: D-leucine
- Also called
- D-leu
- Systematic name
- (2R)-2-azaniumyl-4-methylpentanoate