Proteins/UNIPROT:Q9NYV6

RRN3

ProteinUNIPROT:Q9NYV6

Required for efficient transcription initiation by RNA polymerase I (Pol I). Required for the formation of the competent pre-initiation complex (PIC)..

Function from UniProtKB (Q9NYV6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

34 statements

34 statements · 3 reference databases · Subject: RRN3 · Sources: Hetionet, Reactome, WikiPathways

Order

RRN3 covaries with REDIC1ProteinHetionet hetionet:covaries:283461-54700Inferred only
RRN3 covaries with RHEBL1ProteinHetionet hetionet:covaries:121268-54700Inferred only
CCNE1 interacts with RRN3ProteinHetionet hetionet:interacts:54700-898Inferred only
CDK2 interacts with RRN3ProteinHetionet hetionet:interacts:1017-54700Inferred only
EIF3L interacts with RRN3ProteinHetionet hetionet:interacts:51386-54700Inferred only
MYO1C interacts with RRN3ProteinHetionet hetionet:interacts:4641-54700Inferred only
POLR1A interacts with RRN3ProteinHetionet hetionet:interacts:25885-54700Inferred only
RRN3 interacts with POLR1BProteinHetionet hetionet:interacts:54700-84172Inferred only
RRN3 interacts with POLR1EProteinHetionet hetionet:interacts:54700-64425Inferred only
PPP2R2A interacts with RRN3ProteinHetionet hetionet:interacts:54700-5520Inferred only
SET interacts with RRN3ProteinHetionet hetionet:interacts:54700-6418Inferred only
TAF1A interacts with RRN3ProteinHetionet hetionet:interacts:54700-9015Inferred only

Show the remaining 22

TAF1B interacts with RRN3ProteinHetionet hetionet:interacts:54700-9014Inferred only
UBC interacts with RRN3ProteinHetionet hetionet:interacts:54700-7316Inferred only
UBD interacts with RRN3ProteinHetionet hetionet:interacts:10537-54700Inferred only
RRN3 participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
RRN3 participates in RNA Polymerase I Promoter EscapePathwayReactome R-HSA-73772Inferred only
RRN3 participates in RNA Polymerase I TranscriptionPathwayReactome R-HSA-73864Inferred only
RRN3 participates in RNA Polymerase I Transcription InitiationPathwayReactome R-HSA-73762Inferred only
RRN3 participates in Transcription activation RNA polymerase I and KAT2A B and inhibition NuRD complex PathwayWikiPathways WP5565Inferred only
BLM increases the expression of RRN3ProteinHetionet hetionet:regulates:641-54700Inferred only
C1QTNF6 increases the expression of RRN3ProteinHetionet hetionet:regulates:114904-54700Inferred only
CDK11B increases the expression of RRN3ProteinHetionet hetionet:regulates:984-54700Inferred only
DUT increases the expression of RRN3ProteinHetionet hetionet:regulates:1854-54700Inferred only
FAH increases the expression of RRN3ProteinHetionet hetionet:regulates:2184-54700Inferred only
GNAI2 increases the expression of RRN3ProteinHetionet hetionet:regulates:2771-54700Inferred only
PARP2 decreases the expression of RRN3ProteinHetionet hetionet:regulates:10038-54700Inferred only
PGBD1 increases the expression of RRN3ProteinHetionet hetionet:regulates:84547-54700Inferred only
POLB increases the expression of RRN3ProteinHetionet hetionet:regulates:5423-54700Inferred only
RAN increases the expression of RRN3ProteinHetionet hetionet:regulates:5901-54700Inferred only
SNRPD1 increases the expression of RRN3ProteinHetionet hetionet:regulates:6632-54700Inferred only
SNW1 increases the expression of RRN3ProteinHetionet hetionet:regulates:22938-54700Inferred only
TP53 increases the expression of RRN3ProteinHetionet hetionet:regulates:7157-54700Inferred only
TRIM62 increases the expression of RRN3ProteinHetionet hetionet:regulates:55223-54700Inferred only

Other names

3 names

Resolves to: RRN3

Also called: TIF-IATIFIATranscription initiation factor IA

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