Compound

3-oxotetradecanoyl-CoA

Tetraanion of 3-oxotetradecanoyl-CoA arising from deprotonation of the phosphate and diphosphate functions; principal microspecies at pH 7.3.

Definition from ChEBI (CHEBI:62543), read 2026-09-23. CC BY 4.0.

CHEBI:62543ChEBI

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Structure

2D depiction

No three-dimensional record for this entry.

Class: Organic compound, anion
Formula: C35H56N7O18P3S
Mass: 987.853 g/mol
Charge: -4
InChIKey: IQNFBGHLIVBNOU-QSGBVPJFSA-J
SMILES: CCCCCCCCCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

6 entities

6 entities reached.

0 reported hops6 assembled from the scaffold

What the reference databases state

Statements

10 statements

10 statements · 2 reference databases · Subject: 3-oxotetradecanoyl-CoA · Sources: Human-GEM, Rhea

Order

3-oxotetradecanoyl-CoA is converted to dodecanoyl-CoACompoundRhea RHEA:31091Inferred only
dodecanoyl-CoA is converted to 3-oxotetradecanoyl-CoACompoundRhea RHEA:60140Inferred only
3-oxotetradecanoyl-CoA is a substrate of ACAA1ProteinHuman-GEM MAR03085Inferred only
3-oxotetradecanoyl-CoA is a substrate of ACAA1ProteinRhea RHEA:31091Inferred only
3-oxotetradecanoyl-CoA is a substrate of ACAA2ProteinHuman-GEM MAR03132Inferred only
3-oxotetradecanoyl-CoA is a substrate of HADHAProteinHuman-GEM MAR03132Inferred only
3-oxotetradecanoyl-CoA is a substrate of HADHBProteinRhea RHEA:31091Inferred only
3-oxotetradecanoyl-CoA is a substrate of HADHBProteinHuman-GEM MAR03132Inferred only
3-oxotetradecanoyl-CoA is a substrate of MYO5BProteinHuman-GEM MAR03085Inferred only
3-oxotetradecanoyl-CoA is a substrate of SCP2ProteinRhea RHEA:31091Inferred only

Reactions

8 reactions

MAM00178x+NAD(+)3-oxotetradecanoyl-CoA+proton+NADH(2-)
Catalysed by ACAA1 & HSD17B4 & EHHADH
Reaction pageLeft to rightBalancedEC 1.1.1.35, 1.1.1.211peroxisome
Human-GEM MAR03084CC BY 4.0Reference data
3-oxotetradecanoyl-CoA+CHEBI:1146900CHEBI:15351+dodecanoyl-CoA
Catalysed by ACAA1 & MYO5B
Reaction pageLeft to rightBalancedEC 2.3.1.16peroxisome
Human-GEM MAR03085CC BY 4.0Reference data
MAM00178m+NAD(+)3-oxotetradecanoyl-CoA+proton+NADH(2-)
Catalysed by HADHA & HADH & HSD17B10
Reaction pageLeft to rightBalancedEC 1.1.1.35, 1.1.1.211mitochondrial matrix
Human-GEM MAR03130CC BY 4.0Reference data
3-oxotetradecanoyl-CoA+CHEBI:1146900CHEBI:15351+dodecanoyl-CoA
Catalysed by HADHA & ACAA2 & HADHB
Reaction pageLeft to rightBalancedEC 2.3.1.16, 1.1.1.211mitochondrial matrix
Human-GEM MAR03132CC BY 4.0Reference data
dodecanoyl-CoA+acetyl-CoA3-oxotetradecanoyl-CoA+coenzyme A(4-)
Catalysed by ACAA1 or SCP2 or HADHB
Reaction pageRight to leftBalanced
Rhea RHEA:31091CC BY 4.0Reference data
CHEBI:62614+NAD(1-)3-oxotetradecanoyl-CoA+NADH(2-)+hydron
Catalysed by HADHA
Reaction pageLeft to rightBalanced
Rhea RHEA:31167CC BY 4.0Reference data
dodecanoyl-CoA+malonyl-CoA+hydron3-oxotetradecanoyl-CoA+carbon dioxide+coenzyme A(4-)
Catalysed by ELOVL6
Reaction pageLeft to rightBalanced
Rhea RHEA:60140CC BY 4.0Reference data
CHEBI:74277+NAD(1-)3-oxotetradecanoyl-CoA+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:78667CC BY 4.0Reference data

Other names

5 names

Resolves to: 3-oxotetradecanoyl-CoA

Also called: 3-oxo-myristoyl-CoA(4-)3-oxo-myristoyl-CoA(4−)3-oxomyristoyl-CoA(4-)3-oxomyristoyl-CoA(4−)
Systematic name: 3'-phosphonatoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(3-oxotetradecanoyl)sulfanyl]ethyl}amino)propyl]amino}butyl] diphosphate}