Compound

3-oxododecanoyl-CoA

An acyl-CoA(4−) oxoanion arising from deprotonation of the phosphate and diphosphate OH groups of 3-oxolauroyl-CoA; major species at pH 7.3.

Definition from ChEBI (CHEBI:62615), read 2026-09-23. CC BY 4.0.

CHEBI:62615ChEBI

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Structure

2D depiction

No three-dimensional record for this entry.

Class: Organic compound, anion
Formula: C33H52N7O18P3S
Mass: 959.799 g/mol
Charge: -4
InChIKey: HQANBZHVWIDNQZ-GMHMEAMDSA-J
SMILES: CCCCCCCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

6 entities

6 entities reached.

0 reported hops6 assembled from the scaffold

What the reference databases state

Statements

9 statements

9 statements · 2 reference databases · Subject: 3-oxododecanoyl-CoA · Sources: Human-GEM, Rhea

Order

3-oxododecanoyl-CoA is converted to decanoyl-CoACompoundRhea RHEA:31183Inferred only
3-oxododecanoyl-CoA is a substrate of ACAA1ProteinHuman-GEM MAR03089Inferred only
3-oxododecanoyl-CoA is a substrate of ACAA1ProteinRhea RHEA:31183Inferred only
3-oxododecanoyl-CoA is a substrate of ACAA2ProteinHuman-GEM MAR03139Inferred only
3-oxododecanoyl-CoA is a substrate of HADHAProteinHuman-GEM MAR03139Inferred only
3-oxododecanoyl-CoA is a substrate of HADHBProteinHuman-GEM MAR03139Inferred only
3-oxododecanoyl-CoA is a substrate of HADHBProteinRhea RHEA:31183Inferred only
3-oxododecanoyl-CoA is a substrate of MYO5BProteinHuman-GEM MAR03089Inferred only
3-oxododecanoyl-CoA is a substrate of SCP2ProteinRhea RHEA:31183Inferred only

Reactions

9 reactions

MAM00174x+NAD(+)3-oxododecanoyl-CoA+proton+NADH(2-)
Catalysed by ACAA1 & HSD17B4 & EHHADH
Reaction pageLeft to rightBalancedEC 1.1.1.35, 1.1.1.211peroxisome
Human-GEM MAR03088CC BY 4.0Reference data
3-oxododecanoyl-CoA+CHEBI:1146900CHEBI:15351+decanoyl-CoA
Catalysed by ACAA1 & MYO5B
Reaction pageLeft to rightBalancedEC 2.3.1.16peroxisome
Human-GEM MAR03089CC BY 4.0Reference data
MAM00174m+NAD(+)3-oxododecanoyl-CoA+proton+NADH(2-)
Catalysed by HADHA & HADH & HSD17B10
Reaction pageLeft to rightBalancedEC 1.1.1.35, 1.1.1.211mitochondrial matrix
Human-GEM MAR03137CC BY 4.0Reference data
3-oxododecanoyl-CoA+CHEBI:1146900CHEBI:15351+decanoyl-CoA
Catalysed by HADHA & ACAA2 & HADHB
Reaction pageLeft to rightBalancedEC 2.3.1.16, 1.1.1.211mitochondrial matrix
Human-GEM MAR03139CC BY 4.0Reference data
CHEBI:62558+NAD(1-)3-oxododecanoyl-CoA+NADH(2-)+hydron
Catalysed by HADHA
Reaction pageLeft to rightBalanced
Rhea RHEA:31179CC BY 4.0Reference data
decanoyl-CoA+acetyl-CoA3-oxododecanoyl-CoA+coenzyme A(4-)
Catalysed by ACAA1 or SCP2 or HADHB
Reaction pageRight to leftBalanced
Rhea RHEA:31183CC BY 4.0Reference data
CHEBI:74276+NADP(3-)3-oxododecanoyl-CoA+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:45848CC BY 4.0Reference data
3-oxododecanoyl-CoA+waterCHEBI:29743+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:65216CC BY 4.0Reference data
CHEBI:74276+NAD(1-)3-oxododecanoyl-CoA+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:78671CC BY 4.0Reference data

Other names

3 names

Resolves to: 3-oxododecanoyl-CoA

Also called: 3-oxododecanoyl-CoA(4-)3-oxododecanoyl-CoA(4−)
Systematic name: 3'-phosphonatoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(3-oxododecanoyl)sulfanyl]ethyl}amino)propyl]amino}butyl] diphosphate}