Compound

3-oxo-(7Z-hexadecenoyl)-CoA

A 3-oxo-fatty acyl CoA(4−) obtained by deprotonation of phosphate and diphosphate OH groups of (7Z)-3-oxohexadecenoyl-CoA; major species at pH 7.3.

Definition from ChEBI (CHEBI:87719), read 2026-09-23. CC BY 4.0.

CHEBI:87719ChEBI

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Structure

2D depiction

Class: Organic compound, anion
Formula: C37H58N7O18P3S
Mass: 1013.891 g/mol
Charge: -4
InChIKey: BUCIFQOXNYHEOO-YDGGZUKGSA-J
SMILES: CCCCCCCC/C=CCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

5 entities

5 entities reached.

0 reported hops5 assembled from the scaffold

What the reference databases state

Chemical structure

(5Z)-tetradecenoyl-CoA has the functional parent 3-oxo-(7Z-hexadecenoyl)-CoACompoundChEBI CHEBI:84650Inferred only

Statements

6 statements

6 statements · 2 reference databases · Subject: 3-oxo-(7Z-hexadecenoyl)-CoA · Sources: Human-GEM, Rhea

Order

3-oxo-(7Z-hexadecenoyl)-CoA is a substrate of ACAA1ProteinHuman-GEM MAR03349Inferred only
3-oxo-(7Z-hexadecenoyl)-CoA is a substrate of ACAA2ProteinHuman-GEM MAR03233Inferred only
3-oxo-(7Z-hexadecenoyl)-CoA is a substrate of HADHAProteinHuman-GEM MAR03233Inferred only
3-oxo-(7Z-hexadecenoyl)-CoA is a substrate of HADHBProteinHuman-GEM MAR03233Inferred only
3-oxo-(7Z-hexadecenoyl)-CoA is a substrate of HADHBProteinRhea RHEA:47444Inferred only
3-oxo-(7Z-hexadecenoyl)-CoA is a substrate of MYO5BProteinHuman-GEM MAR03349Inferred only

Reactions

7 reactions

MAM00172m+NAD(+)3-oxo-(7Z-hexadecenoyl)-CoA+proton+NADH(2-)
Catalysed by HADHA & HADH & HSD17B10
Reaction pageLeft to rightBalancedEC 1.1.1.35, 1.1.1.211GO:0005759
Human-GEM MAR03232CC BY 4.0Reference data
3-oxo-(7Z-hexadecenoyl)-CoA+CHEBI:1146900(5Z)-tetradecenoyl-CoA+CHEBI:15351
Catalysed by HADHA & ACAA2 & HADHB
Reaction pageLeft to rightBalancedEC 2.3.1.16, 1.1.1.211GO:0005759
Human-GEM MAR03233CC BY 4.0Reference data
MAM00172x+NAD(+)3-oxo-(7Z-hexadecenoyl)-CoA+proton+NADH(2-)
Catalysed by ACAA1 & HSD17B4 & EHHADH
Reaction pageLeft to rightBalancedEC 1.1.1.35, 1.1.1.211GO:0005777
Human-GEM MAR03348CC BY 4.0Reference data
3-oxo-(7Z-hexadecenoyl)-CoA+CHEBI:1146900(5Z)-tetradecenoyl-CoA+CHEBI:15351
Catalysed by ACAA1 & MYO5B
Reaction pageLeft to rightBalancedEC 2.3.1.16GO:0005777
Human-GEM MAR03349CC BY 4.0Reference data
CHEBI:87718+NAD(1-)3-oxo-(7Z-hexadecenoyl)-CoA+NADH(2-)+hydron
Catalysed by HADHA
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47440CC BY 4.0Reference data
3-oxo-(7Z-hexadecenoyl)-CoA+coenzyme A(4-)(5Z)-tetradecenoyl-CoA+acetyl-CoA
Catalysed by HADHB
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47444CC BY 4.0Reference data
CHEBI:235453+NAD(1-)3-oxo-(7Z-hexadecenoyl)-CoA+NADH(2-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:86187CC BY 4.0Reference data

Other names

6 names

Resolves to: 3-oxo-(7Z-hexadecenoyl)-CoA

Also called: (7Z)-3-ketohexadecenoyl-CoA(4-)(7Z)-3-ketohexadecenoyl-CoA(4−)(7Z)-3-ketohexadecenoyl-coenzyme A(4-)(7Z)-3-ketohexadecenoyl-coenzyme A(4−)(7Z)-3-oxohexadecenoyl-coenzyme A(4-)(7Z)-3-oxohexadecenoyl-coenzyme A(4−)