Compound

3-oxo-(9Z-octadecenoyl)-CoA

A monounsaturated fatty acyl-CoA(4−) obtained by deprotonation of the phosphate and diphosphate OH groups of 3-oxooleoyl-CoA; major species at pH 7.3.

Definition from ChEBI (CHEBI:87695), read 2026-09-23. CC BY 4.0.

CHEBI:87695ChEBI

Open in the graph

Structure

2D depiction

Class: Organic compound, anion
Formula: C39H62N7O18P3S
Mass: 1041.945 g/mol
Charge: -4
InChIKey: AVEYYKDEKGJVBU-BPMMELMSSA-J
SMILES: CCCCCCCC/C=CCCCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

6 entities

6 entities reached.

0 reported hops6 assembled from the scaffold

What the reference databases state

Statements

13 statements

13 statements · 2 reference databases · Subject: 3-oxo-(9Z-octadecenoyl)-CoA · Sources: Human-GEM, Rhea

Order

(3S)-hydroxy-(9Z-octadecenoyl)-CoA is converted to 3-oxo-(9Z-octadecenoyl)-CoACompoundHuman-GEM MAR03228Inferred only
(3S)-hydroxy-(9Z-octadecenoyl)-CoA is converted to 3-oxo-(9Z-octadecenoyl)-CoACompoundHuman-GEM MAR03344Inferred only
(3S)-hydroxy-(9Z-octadecenoyl)-CoA is converted to 3-oxo-(9Z-octadecenoyl)-CoACompoundRhea RHEA:47428Inferred only
3-oxo-(9Z-octadecenoyl)-CoA is converted to (7Z)-hexadecenoyl-CoACompoundRhea RHEA:47400Inferred only
3-oxo-(9Z-octadecenoyl)-CoA is a substrate of ACAA1ProteinHuman-GEM MAR03345Inferred only
3-oxo-(9Z-octadecenoyl)-CoA is a substrate of ACAA2ProteinHuman-GEM MAR03229Inferred only
3-oxo-(9Z-octadecenoyl)-CoA is a substrate of ACAA2ProteinHuman-GEM MAR02381Inferred only
3-oxo-(9Z-octadecenoyl)-CoA is a substrate of HADHAProteinHuman-GEM MAR03229Inferred only
3-oxo-(9Z-octadecenoyl)-CoA is a substrate of HADHBProteinRhea RHEA:47400Inferred only
3-oxo-(9Z-octadecenoyl)-CoA is a substrate of HADHBProteinHuman-GEM MAR02381Inferred only
3-oxo-(9Z-octadecenoyl)-CoA is a substrate of HADHBProteinHuman-GEM MAR03229Inferred only
3-oxo-(9Z-octadecenoyl)-CoA is a substrate of MYO5BProteinHuman-GEM MAR03345Inferred only

Show the remaining 1

3-oxo-(9Z-octadecenoyl)-CoA is a substrate of SCP2ProteinRhea RHEA:47400Inferred only

Reactions

8 reactions

3-oxo-(9Z-octadecenoyl)-CoA+CHEBI:1146900CHEBI:15351+(9Z)-hexadecenoyl-CoA
Catalysed by HADHB or ACAA2
Reaction pageLeft to rightBalancedEC 2.3.1.86mitochondrial matrix
Human-GEM MAR02381CC BY 4.0Reference data
(3S)-hydroxy-(9Z-octadecenoyl)-CoA+NAD(+)3-oxo-(9Z-octadecenoyl)-CoA+proton+NADH(2-)
Catalysed by HADHA & HADH & HSD17B10
Reaction pageLeft to rightBalancedEC 1.1.1.35, 1.1.1.211mitochondrial matrix
Human-GEM MAR03228CC BY 4.0Reference data
3-oxo-(9Z-octadecenoyl)-CoA+CHEBI:1146900(7Z)-hexadecenoyl-CoA+CHEBI:15351
Catalysed by HADHA & ACAA2 & HADHB
Reaction pageLeft to rightBalancedEC 2.3.1.16, 1.1.1.211mitochondrial matrix
Human-GEM MAR03229CC BY 4.0Reference data
(3S)-hydroxy-(9Z-octadecenoyl)-CoA+NAD(+)3-oxo-(9Z-octadecenoyl)-CoA+proton+NADH(2-)
Catalysed by ACAA1 & HSD17B4 & EHHADH
Reaction pageLeft to rightBalancedEC 1.1.1.35, 1.1.1.211peroxisome
Human-GEM MAR03344CC BY 4.0Reference data
3-oxo-(9Z-octadecenoyl)-CoA+CHEBI:1146900(7Z)-hexadecenoyl-CoA+CHEBI:15351
Catalysed by ACAA1 & MYO5B
Reaction pageLeft to rightBalancedEC 2.3.1.16peroxisome
Human-GEM MAR03345CC BY 4.0Reference data
3-oxo-(9Z-octadecenoyl)-CoA+coenzyme A(4-)(7Z)-hexadecenoyl-CoA+acetyl-CoA
Catalysed by SCP2 or HADHB
Reaction pageLeft to rightBalanced
Rhea RHEA:47400CC BY 4.0Reference data
(3S)-hydroxy-(9Z-octadecenoyl)-CoA+NAD(1-)3-oxo-(9Z-octadecenoyl)-CoA+NADH(2-)+hydron
Catalysed by HADHA
Reaction pageLeft to rightBalanced
Rhea RHEA:47428CC BY 4.0Reference data
CHEBI:235452+NAD(1-)3-oxo-(9Z-octadecenoyl)-CoA+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:86183CC BY 4.0Reference data

Other names

6 names

Resolves to: 3-oxo-(9Z-octadecenoyl)-CoA

Also called: (9Z)-3-oxooctadecenoyl-CoA(4-)(9Z)-3-oxooctadecenoyl-CoA(4−)(9Z)-3-oxooctadecenoyl-coenzyme A(4-)(9Z)-3-oxooctadecenoyl-coenzyme A(4−)3-oxooleoyl-coenzyme A(4-)3-oxooleoyl-coenzyme A(4−)