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Proteins/UNIPROT:Q9H3Q3
Catalyzes the transfer of a sulfate group from 3'-phosphoadenylyl sulfate (PAPS) to the C-3 hydroxyl group of terminal non-reducing beta-galactosyl residues. Acts both on type 1 (Gal-beta-1,3-GlcNAc-R) and type 2 (Gal-beta-1,4-GlcNAc-R) chains with similar efficiency. Displays species-dependent substrate specificity. Participates in galactose sulfation and shows substrate preference for structures such as lactose, lacto-N-tetraose (Lc4), lacto-N-neotetraose (nLc4), the Gal-beta-1,4-GlcNAc-beta unit in mucin core-2, and the cancer antigen Globo H precursor Gal-beta-1,3-GlcNAc-beta-1,3-Gal-R..
Function from UniProtKB (Q9H3Q3), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
125 statements
125 statements · 3 reference databases · Subject: GAL3ST2 · Sources: Hetionet, Human-GEM, WikiPathways
1 reaction
3,3'-diiodo-L-thyronine+3'-phospho-5'-adenylyl sulfate3,3'-diiodo-L-thyronine sulfate+proton+adenosine 3',5'-bismonophosphate
Catalysed by NDST1 or UST or CHST10 or SULT4A1 or CHST7 or HS2ST1 or CHST9 or GAL3ST2 or NDST3 or SULT1B1 or HS6ST3 or GAL3ST4
5 names
Resolves to: GAL3ST2
Reaction pageLeft to rightBalancedEC 2.8.2.-cytosol
Human-GEM MAR06829CC BY 4.0Reference data