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Proteins/UNIPROT:Q9NS84
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. Preferentially acts on mannose-linked GlcNAc. Also able to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency. Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1-4GlcNAc. Catalyzes 6-O-sulfation of beta-benzyl GlcNAc but not alpha- or beta-benzyl GalNAc..
Function from UniProtKB (Q9NS84), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
22 statements
22 statements · 4 reference databases · Subject: CHST7 · Sources: Hetionet, Human-GEM, Reactome, WikiPathways
12 reactions
7 names
Resolves to: CHST7
3,3'-diiodo-L-thyronine+3'-phospho-5'-adenylyl sulfate3,3'-diiodo-L-thyronine sulfate+proton+adenosine 3',5'-bismonophosphate
Catalysed by NDST1 or UST or CHST10 or SULT4A1 or CHST7 or HS2ST1 or CHST9 or GAL3ST2 or NDST3 or SULT1B1 or HS6ST3 or GAL3ST4 and 2 more alternatives
Reaction pageLeft to rightBalancedEC 2.8.2.-cytosol
Human-GEM MAR06829CC BY 4.0Reference data
MAM02230g+3'-phospho-5'-adenylyl sulfateproton+MAM02278g+adenosine 3',5'-bismonophosphate
Catalysed by CHST3 or CHST7 or CHST1
Reaction pageLeft to rightBalance undeterminableEC 2.8.2.17, 2.8.2.21Golgi apparatus
Human-GEM MAR07371CC BY 4.0Reference data
MAM02305g+3'-phospho-5'-adenylyl sulfateproton+MAM02288g+adenosine 3',5'-bismonophosphate
Catalysed by CHST3 or CHST7 or CHST1
Reaction pageLeft to rightBalance undeterminableEC 2.8.2.17, 2.8.2.21Golgi apparatus
Human-GEM MAR07452CC BY 4.0Reference data
MAM02290g+3'-phospho-5'-adenylyl sulfateproton+MAM02303g+adenosine 3',5'-bismonophosphate
Catalysed by CHST3 or CHST7 or CHST1
Reaction pageLeft to rightBalance undeterminableEC 2.8.2.17, 2.8.2.21Golgi apparatus
Human-GEM MAR07481CC BY 4.0Reference data
MAM01518g+23'-phospho-5'-adenylyl sulfateMAM01563g+2proton+2adenosine 3',5'-bismonophosphate
Catalysed by CHST7
Reaction pageLeft to rightBalance undeterminableEC 2.8.2.17Golgi apparatus
Human-GEM MAR07492CC BY 4.0Reference data
MAM01568g+23'-phospho-5'-adenylyl sulfateMAM01532g+2proton+2adenosine 3',5'-bismonophosphate
Catalysed by CHST3 or CHST7 or CHST15
Reaction pageLeft to rightBalance undeterminableEC 2.8.2.17, 2.8.2.33Golgi apparatus
Human-GEM MAR07519CC BY 4.0Reference data
MAM01541g+3'-phospho-5'-adenylyl sulfateMAM01533g+proton+adenosine 3',5'-bismonophosphate
Catalysed by CHST3 or CHST7 or CHST15
Reaction pageLeft to rightBalance undeterminableEC 2.8.2.17, 2.8.2.33Golgi apparatus
Human-GEM MAR07522CC BY 4.0Reference data
MAM01552g+3'-phospho-5'-adenylyl sulfateMAM01553g+proton+adenosine 3',5'-bismonophosphate
Catalysed by CHST3 or CHST7 or CHST15
Reaction pageLeft to rightBalance undeterminableEC 2.8.2.17, 2.8.2.33Golgi apparatus
Human-GEM MAR07537CC BY 4.0Reference data
MAM01565g+3'-phospho-5'-adenylyl sulfateMAM01567g+proton+adenosine 3',5'-bismonophosphate
Catalysed by CHST3 or CHST7 or CHST15
Reaction pageLeft to rightBalance undeterminableEC 2.8.2.17, 2.8.2.33Golgi apparatus
Human-GEM MAR07552CC BY 4.0Reference data
MAM01566g+3'-phospho-5'-adenylyl sulfateMAM01554g+proton+adenosine 3',5'-bismonophosphate
Catalysed by CHST7
Reaction pageLeft to rightBalance undeterminableEC 2.8.2.17Golgi apparatus
Human-GEM MAR07553CC BY 4.0Reference data
CHEBI:57652+n3'-phosphoadenylyl sulfateCHEBI:62065+nadenosine 3',5'-bisphosphate+nhydron
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:11108CC BY 4.0Reference data