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Proteins/UNIPROT:Q6P2H3
Acts as a regulator of centriole duplication through a direct interaction with STIL, a key factor involved in the early steps of centriole formation. The CEP85-STIL protein complex acts as a modulator of PLK4-driven cytoskeletal rearrangements and directional cell motility. Acts as a negative regulator of NEK2 to maintain the centrosome integrity in interphase. Suppresses centrosome disjunction by inhibiting NEK2 kinase activity..
Function from UniProtKB (Q6P2H3), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
77 statements
77 statements · 2 reference databases · Subject: CEP85 · Sources: gene ontology, Hetionet
2 names
Resolves to: CEP85