Proteins/UNIPROT:Q86UQ4

ABCA13

ProteinUNIPROT:Q86UQ4ATP-binding cassette sub-family A member 13

May mediate the cholesterol and gangliosides transport from the plasma membrane to intracellular vesicles in an ATP hydrolysis dependent manner, thus playing a role in their internalization by endocytic retrograde transport and may also participate in the endocytosis of synaptic vesicle in cortical neurons..

Function from UniProtKB (Q86UQ4), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

24 statements

24 statements · 5 reference databases · Subject: ABCA13 · Sources: Bgee, gene ontology, Hetionet, Reactome, Rhea

Order

C1orf226 covaries with ABCA13ProteinHetionet hetionet:covaries:154664-400793Inferred only
COBL covaries with ABCA13ProteinHetionet hetionet:covaries:154664-23242Inferred only
DDC covaries with ABCA13ProteinHetionet hetionet:covaries:154664-1644Inferred only
ABCA13 covaries with FCRL1ProteinHetionet hetionet:covaries:115350-154664Inferred only
FIGNL1 covaries with ABCA13ProteinHetionet hetionet:covaries:154664-63979Inferred only
ABCA13 covaries with LGR6ProteinHetionet hetionet:covaries:154664-59352Inferred only
MCPH1 covaries with ABCA13ProteinHetionet hetionet:covaries:154664-79648Inferred only
PAXIP1 covaries with ABCA13ProteinHetionet hetionet:covaries:154664-22976Inferred only
ABCA13 covaries with PTPRCProteinHetionet hetionet:covaries:154664-5788Inferred only
ABCA13 covaries with RNASEH1ProteinHetionet hetionet:covaries:154664-246243Inferred only
TSC1 covaries with ABCA13ProteinHetionet hetionet:covaries:154664-7248Inferred only
ABCA13 covaries with URB2ProteinHetionet hetionet:covaries:154664-9816Inferred only

Show the remaining 12

ABCA13 is expressed in bronchial epithelial cellCell typeBgee ENSG00000179869Inferred only
ABCA13 is expressed in bronchusAnatomyBgee ENSG00000179869Inferred only
ABCA13 is expressed in epithelium of nasopharynxAnatomyBgee ENSG00000179869Inferred only
APOA1 interacts with ABCA13ProteinHetionet hetionet:interacts:154664-335Inferred only
APOA2 interacts with ABCA13ProteinHetionet hetionet:interacts:154664-336Inferred only
CUL3 interacts with ABCA13ProteinHetionet hetionet:interacts:154664-8452Inferred only
ABCA13 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
ABCA13 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
ABCA13 participates in Neutrophil degranulationPathwayReactome R-HSA-6798695Inferred only
ABCA13 regulates positive regulation of cholesterol transportBiological processgene ontology Q86UQ4|GO:0032376Inferred only
ABCA13 regulates positive regulation of synaptic vesicle endocytosisBiological processgene ontology Q86UQ4|GO:1900244Inferred only
cholesterol is transported by ABCA13CompoundRhea RHEA:39051Inferred only

Reactions

1 reaction

cholesterol+ATP(4-)+watercholesterol+ADP(3-)+hydrogenphosphate+hydron
Transported by ABCA8 or ABCA1 or ABCG1 or ABCA13 or ABCA5 or ABCA3 or ABCG4 or ABCG8 or ABCG5
Reaction pageLeft to rightBalanced

Other names

1 name

Resolves to: ABCA13

Also called: ATP-binding cassette sub-family A member 13

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