hexadecanoate
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
229 compounds within 3 steps: 8 in 1, 73 in 2, 148 in 3
Two steps
- 1'-[1-acyl-2-hexadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-hexadecanoyl-sn-glycero-3-phospho]-glycerolReach from here →
- hexadecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 16-hydroxyhexadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
- Fatty Acid Omega Oxidation (W-Ohc16->C16Dc)
Catalysed by CYP4A11, CYP4V2, CYP4F11, ADH5 and 1 morecytosol
- 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-2-hexadecanoyl-sn-glycero-3-phospho]-glycerolReach from here →
- hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
- 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA = 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-2-hexadecanoyl-sn-glycero-3-phospho]-glycerol + CoA
Three steps
- hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
- (R)-carnitine + hexadecanoyl-CoA = O-hexadecanoyl-(R)-carnitine + CoA
- palmitoyl-CoA:L-carnitine O-palmitoyltransferase
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 10 moreperoxisomeOne of 12 routes