docosanoyl-CoA
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
625 compounds within 3 steps: 9 in 1, 153 in 2, 463 in 3
Three steps
- Docosanoyl-CoA hydrolase
- Octanoyl-CoA:L-carnitine O-octanoyltransferase
- octanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by BAAT, ACOT6, CROT, LPCAT1cytosol, mitochondrial matrix
- Fatty Acid Beta Oxidation (C22->C20), Peroxisomal
- eicosanoyl-CoA + 2 NADPH + 2 H(+) = eicosan-1-ol + 2 NADP(+) + CoA
- eicosan-1-ol + (9Z)-octadecenoyl-CoA = 1-O-eicosanyl (9Z)-octadecenoate + CoA
Catalysed by ACAA1, HSD17B4, EHHADH, ACOX1 and 3 moreperoxisome
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerolReach from here →
- Docosanoyl-CoA hydrolase
- Octanoyl-CoA:L-carnitine O-octanoyltransferase
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by BAAT, ACOT6, CROT, LCLAT1cytosol, mitochondrial matrix
- 1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
- Docosanoyl-CoA hydrolase
- Octanoyl-CoA:L-carnitine O-octanoyltransferase
- 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by BAAT, ACOT6, CROT, LCLAT1cytosol, mitochondrial matrix
- Docosanoyl-CoA hydrolase
- long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
- ELOVL fatty acid elongase (trans-2-cis,cis,cis-8,11,14-eicosatetraenoyl-CoA)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol, endoplasmic reticulumOne of 2 routes
- acyl-CoA pool formation and breakdown
- 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a fatty acid + H(+)
Catalysed by LCLAT1, LPCAT1, GPAM, PLA2G15 and 1 morecytosolOne of 2 routes
- Docosanoyl-CoA hydrolase
- Carnitine O-Palmitoyltransferase
- carnitine O-palmitoyltransferase (dodecanoylcarnitine)
Catalysed by BAAT, ACOT6, CPT1A, CPT1C and 1 morecytosolOne of 11 routes
Catalysed by BAAT, ACOT6cytosol, extracellular spaceOne of 13 routes
Catalysed by BAAT, ACOT6cytosol, extracellular spaceOne of 13 routes
Catalysed by BAAT, ACOT6cytosol, extracellular spaceOne of 13 routes
Catalysed by BAAT, ACOT6cytosol, extracellular spaceOne of 14 routes
Catalysed by BAAT, ACOT6, SLC27A2, ACOT2cytosol, peroxisomeOne of 2 routes
- acyl-CoA pool formation and breakdown
- a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
- a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by LPCAT4cytosol
- Docosanoyl-CoA hydrolase
- Octanoyl-CoA:L-carnitine O-octanoyltransferase
- a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octanoyl-CoA = 1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by BAAT, ACOT6, CROT, LPCAT4cytosol, mitochondrial matrix
- Docosanoyl-CoA hydrolase
- long-chain-fatty-acid-CoA ligase (palmitolate)
- medium-chain acyl-CoA dehydrogenase (palmitoleoyl-CoA)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 10 morecytosol, mitochondrial matrixOne of 3 routes
- Docosanoyl-CoA hydrolase
- long-chain-fatty-acid-CoA ligase (margaric acid)
- medium-chain acyl-CoA dehydrogenase (heptadecanoyl-CoA)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 10 morecytosol, mitochondrial matrixOne of 2 routes
- Docosanoyl-CoA hydrolase
- Transport of octadecenoyl-CoA into Mitochondrial Matrix
- medium-chain acyl-CoA dehydrogenase (oleoyl-CoA)
Catalysed by BAAT, ACOT6, CPT1A, CPT1C and 5 morecytosol, mitochondrial matrixOne of 2 routes
- Docosanoyl-CoA hydrolase
- acyl-CoA:sphingosine N-acyltransferase
- N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
Catalysed by BAAT, ACOT6, ASAH1, ACER2 and 3 morecytosol, Golgi apparatus
Catalysed by BAAT, ACOT6cytosol, extracellular spaceOne of 12 routes
- acyl-CoA pool formation and breakdown
- a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
- N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol
- acyl-CoA pool formation and breakdown
- a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
- N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-sphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 2 morecytosol
- acyl-CoA pool formation and breakdown
- sphingosine N-acyltransferase (sphinganine)
- an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by CERS1, CERS6, CERS3, CERS5 and 4 morecytosolOne of 2 routes
- acyl-CoA pool formation and breakdown
- a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
- N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-(4R)-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 2 morecytosol
- acyl-CoA pool formation and breakdown
- a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
- an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 2 morecytosol
Catalysed by BAAT, ACOT6cytosol, extracellular spaceOne of 13 routes
- Docosanoyl-CoA hydrolase
- N-acetylglutamate synthase (N-acetyl-L-cysteine)
- Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
Catalysed by BAAT, ACOT6, NAGS, MOCOScytosol, mitochondrial matrix
- Docosanoyl-CoA hydrolase
- long-chain-fatty-acid-CoA ligase (stearate)
- Acyl-CoA:cholesterol O-acyltransferase
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol, endoplasmic reticulumOne of 6 routes