2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate

Catalysed by FAAH, ALOX12Bcytosol

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. Arachidonate:oxygen 8-oxidoreductase

Catalysed by FAAH, ALOX12cytosolOne of 2 routes

1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
2. 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine

Catalysed by FAAH, CES2, ABHD16A, EPHX1 and 8 more

1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
2. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine

Catalysed by FAAH, CES2, ABHD16A, EPHX1 and 8 more

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. fatty acid amide hydrolase (arachidonate)

Catalysed by FAAHcytosol

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. arachidonic acid:oxygen 1-oxidoreductase

Catalysed by FAAH, CYP1A1, CYP1A2, CYP2E1 and 24 morecytosolOne of 3 routes

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by FAAH, CYP2C9cytosol

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by FAAH, CYP1A1, CYP1A2, CYP2C9 and 2 morecytosol

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + A + H2O

Catalysed by FAAH, PTGS2cytosolOne of 2 routes

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + A + H2O

Catalysed by FAAH, PTGS2cytosolOne of 2 routes

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate

Catalysed by FAAH, PTGS2cytosol

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. Arachidonate: oxygen 11-oxidoreductase

Catalysed by FAAH, ALOX12cytosolOne of 2 routes

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. Arachidonate:oxygen oxidoreductase

Catalysed by FAAH, PTGS1, PTGS2cytosol, endoplasmic reticulumOne of 2 routes

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by FAAH, CYP2C9cytosol

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. unspecific monooxygenase (arachidonate)

Catalysed by FAAH, CYP1A1, CYP1A2, CYP2E1 and 24 morecytosolOne of 4 routes

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. unspecific monooxygenase (arachidonate)

Catalysed by FAAH, CYP1A1, CYP1A2, CYP2E1 and 23 morecytosolOne of 3 routes

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoserine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphoserine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

Catalysed by FAAH, ABHD16Acytosol

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

Catalysed by FAAH, ABHD16Acytosol

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

Catalysed by FAAH, ABHD16Acytosol

1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 2 O2 = 2-glyceryl-prostaglandin G2
2. 2-glyceryl-prostaglandin G2 + AH2 = 2-glyceryl-prostaglandin H2 + A + H2O

Catalysed by PTGS2

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (18R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by FAAH, CYP4F8cytosol

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 15-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate

Catalysed by FAAH, ALOX15Bcytosol

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 5-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate

Catalysed by FAAH, ALOX15Bcytosol

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. Arachidonate:CoA ligase (AMP-forming)
3. Arachidonyl-CoA hydrolase

Catalysed by FAAH, SLC27A2, ACSL4, ACSL3 and 10 morecytosolOne of 255 routes

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. Utilized Transport
3. carnitine O-palmitoyltransferase ((9E)-tetradecenoyl-CoA)