Compound
(18R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate
A 18-HETE(1−) that is the conjugate base of 18(R)-HETE, obtained by deprotonation of the carboxy group; major species at pH 7.3.
Definition from ChEBI (CHEBI:90790), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C20H31O3
- Mass
- 319.465 g/mol
- Charge
- -1
- InChIKey
- PPCHNRUZQWLEMF-LFFPGIGVSA-M
- SMILES
- CC[C@@H](O)CC/C=CC/C=CC/C=CC/C=CCCCC(=O)[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
1 statement
1 statement · 1 reference database · Subject: (18R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate · Sources: Rhea
- (18R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate is metabolised by CYP4F8ProteinRhea RHEA:48736Inferred only
Reactions
1 reaction
(5Z,8Z,11Z,14Z)-eicosatetraenoate+reduced [NADPH--hemoprotein reductase]+dioxygen(18R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP4F8
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:48736CC BY 4.0Reference data
Other names
5 names
Resolves to: (18R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate
- Also called
- (18R)-H-(5Z,8Z,11Z,14Z)-ETE(18R)-HETE(18R)-hydroxyarachidonate(5Z,8Z,11Z,14Z,18R)-18-hydroxyicosatetraenoate
- Systematic name
- (5Z,8Z,11Z,14Z,18R)-18-hydroxyicosa-5,8,11,14-tetraenoate