phosphatidylethanolamine
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
383 compounds within 3 steps: 6 in 1, 49 in 2, 328 in 3
Three steps
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- long-chain-fatty-acid-CoA ligase (adrenic acid)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 9 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- cytochrome P450 (arachidonate)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space, endoplasmic reticulumOne of 2 routes
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-(4R)-4-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol
- Phytoceramide amidohydrolase
Catalysed by PIGF, PIGG, SGMS1, SGMS2 and 5 moreendoplasmic reticulum, cytosolOne of 2 routes
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
- N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphoethanolamine
Catalysed by PIGF, PIGG, SELENOI, CEPT1 and 1 moreendoplasmic reticulumOne of 2 routes
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
- a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-homocysteine + H(+)
Catalysed by PIGF, PIGG, SELENOI, CEPT1 and 1 moreendoplasmic reticulum
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)
- a 1-acyl-sn-glycero-3-phosphate + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphate
Catalysed by PIGF, PIGG, DGKI, DGKA and 10 moreendoplasmic reticulum
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- long-chain-fatty-acid-CoA ligase (cerotic acid)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 8 routes
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)
- a 1,2-diacyl-sn-glycero-3-phosphate + H2O = a 2-acyl-sn-glycerol 3-phosphate + a fatty acid + H(+)
Catalysed by PIGF, PIGG, DGKI, DGKA and 10 moreendoplasmic reticulumOne of 2 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- long-chain-fatty-acid-CoA ligase (lignocerate)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 16 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- long-chain-fatty-acid-CoA ligase (behenic acid)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 13 routes
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
- a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)
Catalysed by PIGF, PIGG, SELENOI, CEPT1 and 1 moreendoplasmic reticulumOne of 2 routes
- phosphatidylethanolamine 2-acylhydrolase
- N-acylsphingosine amidohydrolase
- an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acylsphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 21 morecytosolOne of 2 routes
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular spaceOne of 4 routes
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
- long-chain-fatty-acid-CoA ligase (stearidonic acid)
Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 11 moreendoplasmic reticulum, cytosolOne of 8 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + (9Z)-octadecenoate + H(+)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- N-dodecanoylsphing-4-enine + H2O = dodecanoate + sphing-4-enine
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 18 morecytosol, extracellular space
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- N-tetradecanoylsphing-4-enine + H2O = sphing-4-enine + tetradecanoate
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 17 morecytosol, extracellular space
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- N-octadecanoylsphing-4-enine + H2O = sphing-4-enine + octadecanoate
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 17 morecytosol, extracellular space
- Phosphatidylethanolamine N-Methyltransferase
- ceramide:phosphatidylcholine cholinephosphotransferase
- 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine = 1,2-dihexadecanoyl-sn-glycerol + a sphingomyelin
Catalysed by PEMT, SGMS1, SGMS2mitochondrial matrix, Golgi apparatus
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
- an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphing-4-enine 1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by PIGF, PIGG, SGMS1, SGMS2 and 1 moreendoplasmic reticulumOne of 2 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- (7Z,10Z,13Z,16Z)-docosatetraenoate + ATP + CoA = (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + AMP + diphosphate
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- long-chain-fatty-acid-CoA ligase (EPA)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 12 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- long-chain-fatty-acid-CoA ligase (DPA)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 8 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- long-chain-fatty-acid-CoA ligase (linolenate)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 9 routes
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
- long-chain-fatty-acid-CoA ligase (cis-erucic acid)
Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 11 moreendoplasmic reticulum, cytosolOne of 6 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- long-chain-fatty-acid-CoA ligase (cis-gondoic acid)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 9 routes
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
- long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 11 moreendoplasmic reticulum, cytosolOne of 5 routes
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
- long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)
Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 11 moreendoplasmic reticulum, cytosolOne of 4 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- long-chain-fatty-acid-CoA ligase (nervonic acid)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 8 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- long-chain-fatty-acid-CoA ligase (ximenic acid)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 6 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 7 routes
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
- long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 11 moreendoplasmic reticulum, cytosolOne of 5 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 22 morecytosol, extracellular spaceOne of 10 routes
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
- long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 11 moreendoplasmic reticulum, cytosolOne of 6 routes
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
- long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 11 moreendoplasmic reticulum, cytosolOne of 5 routes
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
- long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 11 moreendoplasmic reticulum, cytosolOne of 5 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- N-(15Z-tetracosenoyl)-sphing-4-enine + H2O = (15Z)-tetracosenoate + sphing-4-enine
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 17 morecytosol, extracellular space
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
- long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 11 moreendoplasmic reticulum, cytosolOne of 6 routes
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
- Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 6 moreendoplasmic reticulum, cytosolOne of 3 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- Arachidonate:oxygen 8-oxidoreductase
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular spaceOne of 2 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + octadecanoate + H(+)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA
- a triacyl-sn-glycerol + H2O = a 2,3-diacyl-sn-glycerol + a fatty acid + H(+)
Catalysed by PIGF, PIGG, DGAT1, MOGAT2 and 5 moreendoplasmic reticulumOne of 2 routes
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- fatty acid amide hydrolase (arachidonate)
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space
- phosphatidylethanolamine 2-acylhydrolase
- (10Z)-heptadecenoic acid formation
- tetracosanoate + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (R)-2-hydroxytetracosanoate + 2 Fe(III)-[cytochrome b5] + H2O
Catalysed by PLA2G10, PLA2G6, PLA2G1B, PLA2G4B and 15 morecytosol, extracellular space
- L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase
- fatty acylamide amidohydrolase
- N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 2-[(5Z,8Z,11Z,14Z)-eicosatetraenoylamino]ethyl (9Z)-octadecenoate + (9Z-octadecenoyl)-sn-glycero-3-phosphocholine
- L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase
- fatty acylamide amidohydrolase
- N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 2-[(5Z,8Z,11Z,14Z)-eicosatetraenoylamino]ethyl (9Z)-octadecenoate + (9Z-octadecenoyl)-sn-glycero-3-phosphocholine
- M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
- an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
- 1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-alkyl-3-acylglycerol + a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by PIGF, PIGG, SGMS1, SGMS2 and 1 moreendoplasmic reticulumOne of 2 routes