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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed

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Catalyst

The evidence graph for human biochemistry. Every edge carries its source, its study design, and a grade computed from both.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Reaction

water+an N-acyl-(4R)-4-hydroxysphinganine(4R)-hydroxysphinganine+fatty acid

Left to right · Balance undeterminable · EC 3.5.1.23

Compartment: GO:0005829

Inferred

Reference data, not a finding. Evidence key

Catalysts

ACER3
ASAH1
ACER1
ACER2
ASAH2

Human-GEM MAR00716·2.0.1·CC BY 4.0Reference data