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3-hydroxyanthranilic acid

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

18 compounds within 3 steps: 2 in 1, 5 in 2, 11 in 3

Does it reach a compound?

One step

superoxideReach from here →
1. catalase (3-hydroxyanthranilate)
Catalysed by CATcytosol
(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehydeReach from here →
1. 3-Hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)
Catalysed by HAAOcytosol

Two steps

11-cis-retinyl hexadecanoateReach from here →
1. catalase (3-hydroxyanthranilate)
2. 11-peroxy-docosahexaenoate to DHA conversion
Catalysed by CATcytosol
quinolinic acidReach from here →
1. 3-Hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)
2. 2-amino-3-carboxymuconate semialdehyde to quinolinate conversion
Catalysed by HAAOcytosol
dehydroascorbic acidReach from here →

Three steps

palmitoyl-CoAReach from here →
Catalysed by CAT, DGAT1, LRAT, AWAT1 and 2 morecytosol
nicotinic acid D-ribonucleotideReach from here →

catalase (3-hydroxyanthranilate)

ascorbate to dehydroascorbic acid conversion

Catalysed by CATcytosol

NAADPHReach from here →

catalase (3-hydroxyanthranilate)
NAADPH + 2 O2 = NAADP(+) + 2 superoxide + H(+)

Catalysed by CAT, NOX5cytosol

3-hydroxyanthranilateReach from here →

3-Hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)
3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde

Catalysed by HAAOcytosol

Catalysed by HAAO, QPRT

cytosol

sulfateReach from here →

3-Hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)
2-amino-3-carboxymuconate semialdehyde to quinolinate conversion
Transport of Quinolinic Acid

Catalysed by HAAO, SLC22A6cytosol, extracellular spaceOne of 2 routes

11-cis-retinolReach from here →

catalase (3-hydroxyanthranilate)
11-peroxy-docosahexaenoate to DHA conversion
Palmitoyl-CoA:retinol O-acyltransferase

Catalysed by CAT, DGAT1, LRAT, AWAT1 and 2 morecytosol

CHEBI:17208Reach from here →

catalase (3-hydroxyanthranilate)
ascorbate to dehydroascorbic acid conversion
7-hydroperoxy-H4-neuroprostane to 7-hydroxy-E4-neuroprostane conversion

Catalysed by CATcytosolOne of 15 routes

all-cis-docosa-4,7,10,13,16,19-hexaenoic acidReach from here →

catalase (3-hydroxyanthranilate)
11-peroxy-docosahexaenoate to DHA conversion
11-peroxy-docosahexaenoate to DHA conversion

Catalysed by CATcytosol

3-hydroxy-L-kynurenineReach from here →

3-Hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)
3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde
3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + L-alanine + H(+)

Catalysed by HAAO, KYNUcytosol

glutathione disulfideReach from here →

catalase (3-hydroxyanthranilate)
ascorbate to dehydroascorbic acid conversion
glutathione:dehydroascorbate oxidoreductase

Catalysed by CATcytosol

D-glucose 6-phosphateReach from here →

catalase (3-hydroxyanthranilate)
NAADPH + 2 O2 = NAADP(+) + 2 superoxide + H(+)
NAADP(+) + D-glucose 6-phosphate = NAADPH + 6-phospho-D-glucono-1,5-lactone + H(+)

Catalysed by CAT, NOX5, G6PDcytosol

NAADP(+)Reach from here →

catalase (3-hydroxyanthranilate)
NAADPH + 2 O2 = NAADP(+) + 2 superoxide + H(+)
NAADPH + O2 + H(+) = NAADP(+) + H2O2

Catalysed by CAT, NOX5, DUOX2, DUOX1cytosolOne of 3 routes

(R)-lipoateReach from here →

catalase (3-hydroxyanthranilate)
ascorbate to dehydroascorbic acid conversion
ascorbate to dehydroascorbic acid conversion

Catalysed by CATcytosol