L-cystine-bis-glycine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

472 compounds within 3 steps: 2 in 1, 77 in 2, 393 in 3

Three steps

pristanoyl-CoAReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. bile acid-CoA: amino acid N-acyltransferase
3. fatty-acid-CoA ligase
Catalysed by DPEP1, DPEP2, BAAT, SLC27A2peroxisome, cytosolOne of 2 routes
undecanoyl-CoAReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. bile acid-CoA: amino acid N-acyltransferase
3. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by DPEP1, DPEP2, BAAT, ACSM4 and 5 moreperoxisome, cytosolOne of 3 routes
a fatty acyl-CoAReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. a fatty acyl-CoA + glycine = an N-(fatty acyl)-glycine + CoA + H(+)
3. a fatty acyl-CoA + glycine = an N-(fatty acyl)-glycine + CoA + H(+)
Catalysed by DPEP1, DPEP2, GLYATL2
(9S)-hydroxy-(10E,12Z)-octadecadienoateReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
3. (9S)-hydroperoxy-(10E,12Z)-octadecadienoate + 2 glutathione = (9S)-hydroxy-(10E,12Z)-octadecadienoate + glutathione disulfide + H2O
Catalysed by DPEP1, DPEP2, GSS, GPX1 and 1 more
ursodeoxycholateReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)
3. transport of GSH and ursodeoxycholate (cytosol to extracellular)
Catalysed by DPEP1, DPEP2, GSS, SLCO1A2 and 1 morecytosol, extracellular spaceOne of 2 routes
prostaglandin G2Reach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)
3. transport of GSH and prostaglandin G2 (cytosol to extracellular)
Catalysed by DPEP1, DPEP2, GSS, SLCO2A1cytosol, extracellular spaceOne of 2 routes
thio-Mo-molybdopterinReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. thioredoxin-disulfide reductase (NADPH) (cystine)
3. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
Catalysed by DPEP1, DPEP2, TXNRD1, TXNRD3 and 2 morecytosol
(12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoateReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
3. (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O
Catalysed by DPEP1, DPEP2, GSS, GPX1 and 2 more
(5Z)-tetradecenoyl-CoAReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. bile acid-CoA: amino acid N-acyltransferase
3. long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by DPEP1, DPEP2, BAAT, SLC27A2 and 7 moreperoxisome, cytosolOne of 8 routes
(3E)-decenoyl-CoAReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. bile acid-CoA: amino acid N-acyltransferase
3. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by DPEP1, DPEP2, BAAT, ACADM and 3 moreperoxisome, mitochondrial matrix
(2R,6)-dimethylheptanoyl-CoAReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. bile acid-CoA: amino acid N-acyltransferase
3. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)
Catalysed by DPEP1, DPEP2, BAAT, HADHA and 2 moreperoxisome, mitochondrial matrix
an N(2)-acyl-L-glutamineReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. transport of glutamine and glycine (cytosol to extracellular)
3. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
Catalysed by DPEP1, DPEP2, SLC7A5, GLYATL1B and 1 moreextracellular space, cytosol
(7Z)-hexadecenoyl-CoAReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. bile acid-CoA: amino acid N-acyltransferase
3. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
Catalysed by DPEP1, DPEP2, BAAT, SLC27A2 and 7 moreperoxisome, cytosolOne of 8 routes
3-methylmalateReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. glycine + 2-oxoglutarate = glyoxylate + L-glutamate
3. propanoyl-CoA + glyoxylate + H2O = 3-methylmalate + CoA + H(+)
Catalysed by DPEP1, DPEP2, AADAT, CLYBL
tricosanoyl-CoAReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. bile acid-CoA: amino acid N-acyltransferase
3. long-chain-fatty-acid-CoA ligase (tricosanoic acid)
Catalysed by DPEP1, DPEP2, BAAT, SLC27A2 and 7 moreperoxisome, cytosolOne of 4 routes
(5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
3. (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + 2 glutathione = (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + glutathione disulfide + H2O
Catalysed by DPEP1, DPEP2, GSS, PTGES and 5 more
(12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoateReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
3. (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O
Catalysed by DPEP1, DPEP2, GSS, GPX1 and 1 more
thromboxane B2Reach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)
3. transport of GSH and thromboxane B2 (cytosol to extracellular)
Catalysed by DPEP1, DPEP2, GSS, SLCO1B1cytosol, extracellular spaceOne of 2 routes
an S-substituted glutathioneReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
3. RX + glutathione = an S-substituted glutathione + a halide anion + H(+)
Catalysed by DPEP1, DPEP2, GSS, GSTT4 and 22 moreOne of 2 routes
(13S)-hydroxy-(9Z,11E)-octadecadienoateReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
3. (13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione = (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O
Catalysed by DPEP1, DPEP2, GSS, GPX1 and 3 more
taurochenodeoxycholateReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)
3. solute carrier organic anion transporter (GSH)
Catalysed by DPEP1, DPEP2, GSS, SLCO1A2 and 2 morecytosol, extracellular spaceOne of 3 routes
2-(1-hydroxyethyl)thiamine diphosphateReach from here →
1. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
2. L-cystine thiocysteine-lyase (deaminating
3. pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)
Catalysed by DPEP1, DPEP2, CTH, PDHA1 and 2 morecytosol, mitochondrial matrix