Proteins/UNIPROT:Q9UQR1

ZNF148

ProteinUNIPROT:Q9UQR1

Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes.

Function from UniProtKB (Q9UQR1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies has a germline basis in ZNF148DiseaseGenCC HGNC:12933|MONDO:0014994Inferred only

Statements

22 statements

22 statements · 2 reference databases · Subject: ZNF148 · Sources: gene ontology, Hetionet

Order

ZNF148 covaries with FBXL19ProteinHetionet hetionet:covaries:54620-7707Inferred only
ZNF148 interacts with CAVIN1ProteinHetionet hetionet:interacts:284119-7707Inferred only
EP300 interacts with ZNF148ProteinHetionet hetionet:interacts:2033-7707Inferred only
HDAC1 interacts with ZNF148ProteinHetionet hetionet:interacts:3065-7707Inferred only
ZNF148 interacts with HDAC3ProteinHetionet hetionet:interacts:7707-8841Inferred only
RXRG interacts with ZNF148ProteinHetionet hetionet:interacts:6258-7707Inferred only
STAT3 interacts with ZNF148ProteinHetionet hetionet:interacts:6774-7707Inferred only
SUMO2 interacts with ZNF148ProteinHetionet hetionet:interacts:6613-7707Inferred only
TP53 interacts with ZNF148ProteinHetionet hetionet:interacts:7157-7707Inferred only
UBC interacts with ZNF148ProteinHetionet hetionet:interacts:7316-7707Inferred only
ZNF148 regulates negative regulation of DNA-templated transcriptionBiological processgene ontology Q9UQR1|GO:0045892Inferred only
ZNF148 regulates negative regulation of gene expressionBiological processgene ontology Q9UQR1|GO:0010629Inferred only

Show the remaining 10

ZNF148 regulates negative regulation of transcription by RNA polymerase IIBiological processgene ontology Q9UQR1|GO:0000122Inferred only
ZNF148 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology Q9UQR1|GO:0006357Inferred only
EIF2B2 increases the expression of ZNF148ProteinHetionet hetionet:regulates:8892-7707Inferred only
HMGCS1 increases the expression of ZNF148ProteinHetionet hetionet:regulates:3157-7707Inferred only
KDR increases the expression of ZNF148ProteinHetionet hetionet:regulates:3791-7707Inferred only
NMT1 increases the expression of ZNF148ProteinHetionet hetionet:regulates:4836-7707Inferred only
PC increases the expression of ZNF148ProteinHetionet hetionet:regulates:5091-7707Inferred only
PRKCZ decreases the expression of ZNF148ProteinHetionet hetionet:regulates:5590-7707Inferred only
SHH decreases the expression of ZNF148ProteinHetionet hetionet:regulates:6469-7707Inferred only
STAT3 decreases the expression of ZNF148ProteinHetionet hetionet:regulates:6774-7707Inferred only

Other names

4 names

Resolves to: ZNF148

Also called: Transcription factor ZBP-89ZBP-89ZBP89Zinc finger DNA-binding protein 89

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