Pathway
Biotin transport and metabolism
Biotin (Btn) is an essential cofactor in a variety of carboxylation reactions. Humans cannot synthesize Btn but it is abundant in the human diet and can be taken up from the intestinal lumen by the SLC5A6 transporter. Its uptake, intracellular translocation, covalent conjugation to apoenzymes, and salvage are described here.
REACT:R-HSA-196780Reactome
What the reference databases state
Statements
11 statements
11 statements · 1 reference database · Subject: Biotin transport and metabolism · Sources: Reactome
- ACACA participates in Biotin transport and metabolismProteinReactome R-HSA-196780Inferred only
- ACACB participates in Biotin transport and metabolismProteinReactome R-HSA-196780Inferred only
- BTD participates in Biotin transport and metabolismProteinReactome R-HSA-196780Inferred only
- HLCS participates in Biotin transport and metabolismProteinReactome R-HSA-196780Inferred only
- MCCC1 participates in Biotin transport and metabolismProteinReactome R-HSA-196780Inferred only
- MCCC2 participates in Biotin transport and metabolismProteinReactome R-HSA-196780Inferred only
- PC participates in Biotin transport and metabolismProteinReactome R-HSA-196780Inferred only
- PCCA participates in Biotin transport and metabolismProteinReactome R-HSA-196780Inferred only
- PCCB participates in Biotin transport and metabolismProteinReactome R-HSA-196780Inferred only
- PDZD11 participates in Biotin transport and metabolismProteinReactome R-HSA-196780Inferred only
- SLC5A6 participates in Biotin transport and metabolismProteinReactome R-HSA-196780Inferred only