Proteins/UNIPROT:Q9NWD9

BEX4

ProteinUNIPROT:Q9NWD9

May play a role in microtubule deacetylation by negatively regulating the SIRT2 deacetylase activity toward alpha-tubulin and thereby participate in the control of cell cycle progression and genomic stability. In absence of reductive stress, acts as a pseudosubstrate for the CRL2(FEM1B) complex: associates with FEM1B via zinc, thereby preventing association between FEM1B and its substrates (By similarity)..

Function from UniProtKB (Q9NWD9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

8 statements

8 statements · 2 reference databases · Subject: BEX4 · Sources: gene ontology, Hetionet

Order

BEX4 covaries with B3GALT4ProteinHetionet hetionet:covaries:56271-8705Inferred only
BEX4 covaries with LPXNProteinHetionet hetionet:covaries:56271-9404Inferred only
BEX4 covaries with PDX1ProteinHetionet hetionet:covaries:3651-56271Inferred only
UBC interacts with BEX4ProteinHetionet hetionet:interacts:56271-7316Inferred only
BEX4 regulates negative regulation of protein ubiquitinationBiological processgene ontology Q9NWD9|GO:0031397Inferred only
BEX4 regulates negative regulation of tubulin deacetylationBiological processgene ontology Q9NWD9|GO:1904428Inferred only
BEX4 regulates regulation of cell migrationBiological processgene ontology Q9NWD9|GO:0030334Inferred only
BEX4 regulates regulation of cell population proliferationBiological processgene ontology Q9NWD9|GO:0042127Inferred only

Other names

5 names

Resolves to: BEX4

Also called: BEX1-like protein 1BEXL1Brain-expressed X-linked protein 4NADE3Nerve growth factor receptor-associated protein 3

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