Proteins/UNIPROT:Q56A73

SPIN4

ProteinUNIPROT:Q56A73

Binds to acetylated and methylated histones, including H3K4me3 and H4K20me3, probably acting as a histone reader that recognizes chromatin marks and mediates downstream cellular effects. Promotes canonical WNT signaling, and is involved in the down-regulation of cell proliferation..

Function from UniProtKB (Q56A73), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

Lui-Jee-Baron syndrome has a germline basis in SPIN4DiseaseGenCC HGNC:27040|MONDO:0957919Inferred only

Statements

15 statements

15 statements · 2 reference databases · Subject: SPIN4 · Sources: gene ontology, Hetionet

Order

SPIN4 covaries with AJUBAProteinHetionet hetionet:covaries:139886-84962Inferred only
SPIN4 covaries with CTSEProteinHetionet hetionet:covaries:139886-1510Inferred only
SPIN4 covaries with MKNK2ProteinHetionet hetionet:covaries:139886-2872Inferred only
SPIN4 covaries with PUM2ProteinHetionet hetionet:covaries:139886-23369Inferred only
SPIN4 covaries with RETREG2ProteinHetionet hetionet:covaries:139886-79137Inferred only
SPIN4 covaries with SMURF2ProteinHetionet hetionet:covaries:139886-64750Inferred only
SPIN4 covaries with STMN3ProteinHetionet hetionet:covaries:139886-50861Inferred only
SPIN4 covaries with SUZ12ProteinHetionet hetionet:covaries:139886-23512Inferred only
SPIN4 covaries with TRAF7ProteinHetionet hetionet:covaries:139886-84231Inferred only
SPIN4 covaries with WNT1ProteinHetionet hetionet:covaries:139886-7471Inferred only
SPIN4 covaries with ZCCHC17ProteinHetionet hetionet:covaries:139886-51538Inferred only
UBC interacts with SPIN4ProteinHetionet hetionet:interacts:139886-7316Inferred only

Show the remaining 3

SPIN4 regulates negative regulation of cell population proliferationBiological processgene ontology Q56A73|GO:0008285Inferred only
SPIN4 regulates positive regulation of canonical Wnt signaling pathwayBiological processgene ontology Q56A73|GO:0090263Inferred only
SPIN4 regulates regulation of DNA-templated transcriptionBiological processgene ontology Q56A73|GO:0006355Inferred only

Other names

1 name

Resolves to: SPIN4

Also called: Spindlin-4

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