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Proteins/UNIPROT:P48735
Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex..
Function from UniProtKB (P48735), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
152 statements
152 statements · 9 reference databases · Subject: IDH2 · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
2 reactions
isocitric acid+NADP(3-)2-oxoglutarate(2-)+carbon dioxide+NADPH(4-)
Catalysed by IDH2
Reaction pageReversibleBalancedEC 1.1.1.42mitochondrial matrix
Human-GEM MAR03958CC BY 4.0Reference data
D-threo-isocitrate+NADP(3-)2-oxoglutarate(2-)+carbon dioxide+NADPH(4-)
Catalysed by IDH1
5 names
Resolves to: IDH2
Reaction pageLeft to rightBalanced
Rhea RHEA:19629CC BY 4.0Reference data