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Proteins/UNIPROT:Q8TB45
Negative regulator of the mTORC1 and mTORC2 complexes: inhibits the protein kinase activity of MTOR, thereby inactivating both complexes. DEPTOR inhibits mTORC1 and mTORC2 to induce autophagy. In contrast to AKT1S1/PRAS40, only partially inhibits mTORC1 activity..
Function from UniProtKB (Q8TB45), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
52 statements
52 statements · 3 reference databases · Subject: DEPTOR · Sources: gene ontology, Hetionet, WikiPathways
3 names
Resolves to: DEPTOR