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Proteins/UNIPROT:Q8IZ52
Non-catalytic component of CHSY1-CHPF2 and CHSY3-CHPF2 chondroitin sulfate synthase complexes. CHPF associates with catalytically active chondroitin synthases (CHSY1/3) within heterodimeric complexes. Plays an essential role for the formation of a stable and functional chondroitin sulfate polymerase complexes..
[Isoform 2]: May facilitate PRKN transport into the mitochondria. In collaboration with PRKN, may enhance cell viability and protect cells from oxidative stress..
Function from UniProtKB (Q8IZ52), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
40 statements
40 statements · 4 reference databases · Subject: CHPF · Sources: Hetionet, Human-GEM, Reactome, WikiPathways
8 reactions
MAM01563g+UDP-alpha-D-glucuronateMAM01564g+proton+UDP
Catalysed by CHPF2 or CHPF or CHSY1 or CHSY3
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.175, 2.4.1.226Golgi apparatus
Human-GEM MAR07493CC BY 4.0Reference data
MAM01564g+CHEBI:16264MAM01565g+proton+UDP
3 names
Resolves to: CHPF
Catalysed by CHPF or CHSY1 or CSGALNACT1 or CSGALNACT2 or CHSY3
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.226Golgi apparatus
Human-GEM MAR07494CC BY 4.0Reference data
MAM01518g+UDP-alpha-D-glucuronateMAM01515g+proton+UDP
Catalysed by CHPF2 or CHPF or CHSY1 or CHSY3
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.175, 2.4.1.226Golgi apparatus
Human-GEM MAR07495CC BY 4.0Reference data
MAM01515g+CHEBI:16264MAM01516g+proton+UDP
Catalysed by CHPF or CHSY1 or CSGALNACT1 or CSGALNACT2 or CHSY3
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.226Golgi apparatus
Human-GEM MAR07496CC BY 4.0Reference data
MAM01532g+UDP-alpha-D-glucuronateMAM01540g+proton+UDP
Catalysed by CHPF2 or CHPF or CHSY1 or CHSY3
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.175, 2.4.1.226Golgi apparatus
Human-GEM MAR07520CC BY 4.0Reference data
MAM01540g+CHEBI:16264MAM01541g+proton+UDP
Catalysed by CHPF or CHSY1 or CSGALNACT1 or CSGALNACT2 or CHSY3
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.226Golgi apparatus
Human-GEM MAR07521CC BY 4.0Reference data
MAM01542g+UDP-alpha-D-glucuronateMAM01551g+proton+UDP
Catalysed by CHPF2 or CHPF or CHSY1 or CHSY3
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.175, 2.4.1.226Golgi apparatus
Human-GEM MAR07535CC BY 4.0Reference data
MAM01551g+CHEBI:16264MAM01552g+proton+UDP
Catalysed by CHPF or CHSY1 or CSGALNACT1 or CSGALNACT2 or CHSY3
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.226Golgi apparatus
Human-GEM MAR07536CC BY 4.0Reference data