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Proteins/UNIPROT:P10746
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme)..
Function from UniProtKB (P10746), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
18 statements
18 statements · 3 reference databases · Subject: UROS · Sources: Hetionet, Reactome, WikiPathways
2 reactions
MAM02151cwater+MAM03128c
Catalysed by UROS
Reaction pageLeft to rightBalancedEC 4.2.1.75cytosol
Human-GEM MAR04748CC BY 4.0Reference data
CHEBI:57845CHEBI:57308+water
Catalysed by UROS
Reaction pageDirection not assertedBalanced
Rhea RHEA:18965CC BY 4.0Reference data
3 names
Resolves to: UROS