Pathway
Class B/2 (Secretin family receptors)
This family is known as Family B (secretin-receptor family, family 2) G-protein-coupled receptors. Family B GPCRs include secretin, calcitonin, parathyroid hormone/parathyroid hormone-related peptides and vasoactive intestinal peptide receptors; all of which activate adenylyl cyclase and the phosphatidyl-inositol-calcium pathway (Harmar AJ, 2001).
REACT:R-HSA-373080Reactome
What the reference databases state
Statements
91 statements
91 statements · 1 reference database · Subject: Class B/2 (Secretin family receptors) · Sources: Reactome
- ADCYAP1 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- ADCYAP1R1 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- ADGRE1 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- ADGRE2 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- ADGRE3 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- ADGRE5 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- ADM participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- ADM2 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- CALCA participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- CALCB participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- CALCR participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- CALCRL participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
Show the remaining 79
- CD55 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- CRH participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- CRHBP participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- CRHR1 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- DHH participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- FZD1 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- FZD10 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- FZD2 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- FZD3 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- FZD4 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- FZD5 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- FZD6 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- FZD7 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- FZD8 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- FZD9 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GCG participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GCGR participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GHRH participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GHRHR participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GIP participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GIPR participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GLP1R participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GLP2R participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNB1 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNB2 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNB3 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNB4 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNB5 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNG10 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNG11 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNG12 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNG13 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNG2 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNG3 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNG4 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNG5 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNG7 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNG8 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNGT1 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- GNGT2 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- IAPP participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- IHH participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- PTCH1 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- PTCH2 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- PTH participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- PTH1R participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- PTH2 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- PTH2R participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- PTHLH participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- RAMP1 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- RAMP2 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- RAMP3 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- SCT participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- SCTR participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- SHH participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- SMO participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- UCN participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- UCN2 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- UCN3 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- VIP participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- VIPR1 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- VIPR2 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT1 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT10A participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT10B participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT11 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT16 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT2 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT2B participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT3 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT3A participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT4 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT5A participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT6 participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT7A participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT7B participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT8A participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT9A participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only
- WNT9B participates in Class B/2 (Secretin family receptors)ProteinReactome R-HSA-373080Inferred only