Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:Q9Y6F9

WNT6

Protein·UNIPROT:Q9Y6F9

Open in the graph

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway..

Function from UniProtKB (Q9Y6F9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

27 statements

27 statements · 4 reference databases · Subject: WNT6 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Search this listOrder

WNT6 covaries with RSPH6AProteinHetionet hetionet:covaries:7475-81492Inferred only
SFRP2 covaries with WNT6ProteinHetionet hetionet:covaries:6423-7475Inferred only
WNT6 interacts with PORCNProteinHetionet hetionet:interacts:64840-7475Inferred only
WNT6 participates in Alzheimer 39 s diseasePathwayWikiPathways WP5124Inferred only
WNT6 participates in Alzheimer 39 s disease and miRNA effectsPathwayWikiPathways WP2059Inferred only
WNT6 participates in Breast cancer pathwayPathwayWikiPathways WP4262Inferred only
WNT6 participates in Cancer pathwaysPathwayWikiPathways WP5434Inferred only
WNT6 participates in Class B/2 (Secretin family receptors)PathwayReactome R-HSA-373080Inferred only
WNT6 participates in DNA damage response only ATM dependent PathwayWikiPathways WP710Inferred only
WNT6 participates in Embryonic stem cell pluripotency pathwaysPathwayWikiPathways WP3931Inferred only
WNT6 participates in Epithelial to mesenchymal transition in colorectal cancerPathwayWikiPathways WP4239Inferred only
WNT6 participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only

Show the remaining 15

WNT6 participates in lncRNA in canonical Wnt signaling and colorectal cancerPathwayWikiPathways WP4258Inferred only
WNT6 participates in lncRNA mediated mechanisms of therapeutic resistancePathwayWikiPathways WP3672Inferred only
WNT6 participates in ncRNAs in Wnt signaling in hepatocellular carcinomaPathwayWikiPathways WP4336Inferred only
WNT6 participates in Osteoblast differentiation and related diseasesPathwayWikiPathways WP4787Inferred only
WNT6 participates in Pleural mesotheliomaPathwayWikiPathways WP5087Inferred only
WNT6 participates in Polycystic kidney disease pathwayPathwayWikiPathways WP2571Inferred only
WNT6 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
WNT6 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
WNT6 participates in Signaling by WNTPathwayReactome R-HSA-195721Inferred only
WNT6 participates in WNT ligand biogenesis and traffickingPathwayReactome R-HSA-3238698Inferred only
WNT6 participates in Wnt signalingPathwayWikiPathways WP428Inferred only
WNT6 participates in Wnt signaling and pluripotencyPathwayWikiPathways WP399Inferred only
WNT6 participates in Wnt signaling in kidney diseasePathwayWikiPathways WP4150Inferred only
WNT6 regulates positive regulation of gene expressionBiological processgene ontology Q9Y6F9|GO:0010628Inferred only
WNT6 regulates positive regulation of tooth mineralizationBiological processgene ontology Q9Y6F9|GO:0070172Inferred only

Other names

2 names

Resolves to: WNT6

Also called: Protein Wnt-6Wnt-6

← Every protein Find it in the graph →