Proteins/UNIPROT:P49190

PTH2R

ProteinUNIPROT:P49190

This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity)..

Function from UniProtKB (P49190), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

14 statements

14 statements · 4 reference databases · Subject: PTH2R · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

CALM1 interacts with PTH2RProteinHetionet hetionet:interacts:5746-805Inferred only
CALM1 interacts with PTH2RProteinHetionet hetionet:interacts:5746-808Inferred only
CALM1 interacts with PTH2RProteinHetionet hetionet:interacts:5746-801Inferred only
PTH2R interacts with GRHPRProteinHetionet hetionet:interacts:5746-9380Inferred only
PTH interacts with PTH2RProteinHetionet hetionet:interacts:5741-5746Inferred only
PTH2R interacts with PTH2ProteinHetionet hetionet:interacts:113091-5746Inferred only
PTH2R participates in Class B/2 (Secretin family receptors)PathwayReactome R-HSA-373080Inferred only
PTH2R participates in G alpha (s) signalling eventsPathwayReactome R-HSA-418555Inferred only
PTH2R participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
PTH2R participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
PTH2R participates in GPCRs class B secretin likePathwayWikiPathways WP334Inferred only
PTH2R participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only

Show the remaining 2

PTH2R participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
PTH2R regulates positive regulation of cold-induced thermogenesisBiological processgene ontology P49190|GO:0120162Inferred only

Other names

3 names

Resolves to: PTH2R

Also called: Parathyroid hormone 2 receptorPTH2 receptorPTHR2

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