(11Z)-octadecenoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

636 compounds within 3 steps: 7 in 1, 156 in 2, 473 in 3

Three steps

1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
1-O-octadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-O-octadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-O-octadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
1-eicosanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-eicosanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-eicosanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
1-hexadecanoyl-2-decanoyl-sn-glycero-3-phosphocholineReach from here →
1. Beta Oxidation Fatty Acid
2. fatty acyl-CoA synthase (N-C10:0CoA)
3. decanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-decanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ACADM, ACADS, LPCAT1mitochondrial matrix, cytosol
1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. tetradecanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerolReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 5 moremitochondrial matrix
a 2,3-diacyl-sn-glycerolReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. acyl-CoA pool formation and breakdown
3. a 2-acylglycerol + an acyl-CoA = a 2,3-diacyl-sn-glycerol + CoA
Catalysed by FADS2, MOGAT2, MOGAT1cytosol
1-dodecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 2-(9Z-octadecenoyl)-glycerol + dodecanoyl-CoA = 1-dodecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol
1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. 2-(9Z-octadecenoyl)-glycerol + tetradecanoyl-CoA = 1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol
1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerolReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1,2-di-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA = 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 4 moremitochondrial matrix
hexadecyl hexadecanoateReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. hexadecan-1-ol + hexadecanoyl-CoA = hexadecyl hexadecanoate + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 4 moremitochondrial matrix
1-hexadecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 3 moremitochondrial matrix
2-hydroxyhexadecyl hexadecanoateReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. hexadecane-1,2-diol + hexadecanoyl-CoA = 2-hydroxyhexadecyl hexadecanoate + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 3 moremitochondrial matrix
1-octadecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
1,2-O,O-dihexadecanoyl-1,2-hexadecanediolReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. hexadecane-1,2-diol + 2 hexadecanoyl-CoA = 1,2-O,O-dihexadecanoyl-1,2-hexadecanediol + 2 CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
eicosan-1-olReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + 2 NADPH + 2 H(+) = eicosan-1-ol + 2 NADP(+) + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol
hexadecyl octadecanoateReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. hexadecan-1-ol + octadecanoyl-CoA = hexadecyl octadecanoate + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerolReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA = 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-hexadecanoyl-sn-glycero-3-phospho]-glycerolReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-hexadecanoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
1-hexadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by FADS2, LPCAT3, MBOAT2, LPCAT1 and 1 morecytosol
2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by FADS2, LPCAT3, MBOAT2, LPCAT1 and 1 morecytosolOne of 3 routes
1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by FADS2, LPCAT3, MBOAT2, LPCAT1 and 1 morecytosol
1-O-alkyl-3-acylglycerolReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. acyl-CoA pool formation and breakdown
3. 1-O-alkylglycerol + an acyl-CoA = 1-O-alkyl-3-acylglycerol + CoA
Catalysed by FADS2, MOGAT2, AWAT2cytosol
hexadecanedioateReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. Production of Hexadecanedioylcarnitine
3. hexadecanedioyl-CoA + H2O = hexadecanedioate + CoA + H(+)
Catalysed by CPT1A, CPT1C, CPT1B, ABCD3cytosol
(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoAReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
3. ELOVL fatty acid elongase (trans-2-cis,cis,cis-8,11,14-eicosatetraenoyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol, endoplasmic reticulumOne of 2 routes
1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
O-dodecanoyl-R-carnitineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. Carnitine O-Palmitoyltransferase
3. carnitine O-palmitoyltransferase (dodecanoylcarnitine)
Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 11 routes
1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerolReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA
3. 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + phosphate
Catalysed by FADS2, AGPAT4, LPIN1cytosol
1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphateReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (DHA)
3. 1-octadecanoyl-sn-glycero-3-phosphate + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
(11Z,14Z)-eicosadienoateReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
3. (11Z,14Z)-eicosadienoyl-CoA hydrolase
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 10 morecytosol
(17Z)-hexacosenoateReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (ximenic acid)
3. Hexacosenoyl-CoA hydrolase
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoateReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (DPA)
3. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol
(7Z,10Z,13Z,16Z)-docosatetraenoateReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (adrenic acid)
3. (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA hydrolase
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosolOne of 2 routes
2,6,10,14-tetramethylpentadecanoateReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. fatty-acid-CoA ligase
3. peroxisomal acyl-CoA thioesterase
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 1 morecytosol, peroxisomeOne of 2 routes
a 1,3-diacyl-sn-glycerolReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. acyl-CoA pool formation and breakdown
3. a 3-acyl-sn-glycerol + an acyl-CoA = a 1,3-diacyl-sn-glycerol + CoA
Catalysed by FADS2, MOGAT1cytosolOne of 2 routes
a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. acyl-CoA pool formation and breakdown
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA
Catalysed by FADS2, LPCAT2, LPCAT1cytosol
a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. acyl-CoA pool formation and breakdown
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by FADS2, LPCAT4cytosol
1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (stearate)
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosol
1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
1-hexadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. Fatty Acid Beta Oxidation (C18:1->C16:1), Mitochondrial
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. a 2-acyl-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by HADHA, ACADVL, HADHB, SCD and 2 moremitochondrial matrix
tetracosan-1-olReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (lignocerate)
3. tetracosanoyl-CoA + 2 NADPH + 2 H(+) = tetracosan-1-ol + 2 NADP(+) + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
trans-2-heptadecenoyl-CoAReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (margaric acid)
3. medium-chain acyl-CoA dehydrogenase (heptadecanoyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 11 morecytosol, mitochondrial matrixOne of 2 routes
(2E,9Z)-octadecadienoyl-CoAReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. Transport of octadecenoyl-CoA into Mitochondrial Matrix
3. medium-chain acyl-CoA dehydrogenase (oleoyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1B, ACADM and 3 morecytosol, mitochondrial matrixOne of 2 routes
(2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoAReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (DHA)
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + O2 = (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + H2O2
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
(9S)-hydroxy-(10E,12Z)-octadecadienoateReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + H2O = (9Z,12Z)-octadecadienoate + CoA + H(+)
3. (9Z,12Z)-octadecadienoate + AH2 + O2 = (9S)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O
Catalysed by FADS2, ACOT8, ACOT2, THEM5 and 3 morecytosol
(9R)-hydroxy-(10E,12Z)-octadecadienoateReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + H2O = (9Z,12Z)-octadecadienoate + CoA + H(+)
3. (9Z,12Z)-octadecadienoate + reduced [NADPH--hemoprotein reductase] + O2 = (9R)-hydroxy-(10E,12Z)-octadecadienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by FADS2, ACOT8, ACOT2, THEM5 and 2 morecytosolOne of 2 routes
N-(9Z-octadecenoyl)-sphing-4-enineReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. acyl-CoA:sphingosine N-acyltransferase
3. N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
Catalysed by CPT1A, CPT1C, CPT1B, ASAH1 and 4 morecytosol, Golgi apparatus
9-cis-retinolReach from here →
1. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
2. Palmitoyl-CoA:retinol O-acyltransferase
3. 11-cis-retinol = 9-cis-retinol
Catalysed by CPT1A, CPT1C, CPT1B, DGAT1 and 5 morecytosol