(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

627 compounds within 3 steps: 5 in 1, 141 in 2, 481 in 3

Three steps

1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholineReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. tetradecanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
1-dodecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 2-(9Z-octadecenoyl)-glycerol + dodecanoyl-CoA = 1-dodecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 8 morecytosol
1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. 2-(9Z-octadecenoyl)-glycerol + tetradecanoyl-CoA = 1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 8 morecytosol
1-octadecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerolReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 2-(9Z-octadecenoyl)-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 8 morecytosol
eicosan-1-olReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + 2 NADPH + 2 H(+) = eicosan-1-ol + 2 NADP(+) + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 8 morecytosol
hexadecyl (9Z)-hexadecenoateReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (palmitolate)
3. hexadecan-1-ol + (9Z)-hexadecenoyl-CoA = hexadecyl (9Z)-hexadecenoate + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 8 morecytosol
hexadecyl octadecanoateReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. hexadecan-1-ol + octadecanoyl-CoA = hexadecyl octadecanoate + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerolReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. Octanoyl-CoA:L-carnitine O-octanoyltransferase
3. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by BAAT, ACOT6, CROT, LCLAT1cytosol, mitochondrial matrix
1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. Octanoyl-CoA:L-carnitine O-octanoyltransferase
3. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by BAAT, ACOT6, CROT, LCLAT1cytosol, mitochondrial matrix
hexadecanedioateReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. Production of Hexadecanedioylcarnitine
3. hexadecanedioyl-CoA + H2O = hexadecanedioate + CoA + H(+)
Catalysed by BAAT, ACOT6, CPT1A, CPT1C and 2 morecytosol
(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoAReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
3. ELOVL fatty acid elongase (trans-2-cis,cis,cis-8,11,14-eicosatetraenoyl-CoA)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol, endoplasmic reticulumOne of 2 routes
2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. acyl-CoA pool formation and breakdown
2. 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
3. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a fatty acid + H(+)
Catalysed by LCLAT1, LPCAT1, GPAM, PLA2G15 and 1 morecytosolOne of 2 routes
3-oxo-(11Z)-octadecenoyl-CoAReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (palmitolate)
3. (9Z)-hexadecenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(11Z)-octadecenoyl-CoA + CO2 + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 8 morecytosol
3-oxo-(13Z)-eicosenoyl-CoAReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
3. (11Z)-octadecenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(13Z)-eicosenoyl-CoA + CO2 + CoA
Catalysed by BAAT, ACOT6, CPT1A, CPT1C and 2 morecytosol
1-O-alkyl-2,3-diacyl-sn-glycerolReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. 1-O-alkyl-2-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-alkyl-2,3-diacyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine
Catalysed by LPGAT1, PLA2G15cytosolOne of 2 routes
1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
O-dodecanoyl-R-carnitineReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. Carnitine O-Palmitoyltransferase
3. carnitine O-palmitoyltransferase (dodecanoylcarnitine)
Catalysed by BAAT, ACOT6, CPT1A, CPT1C and 1 morecytosolOne of 11 routes
1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphateReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphateReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (DHA)
3. 1-octadecanoyl-sn-glycero-3-phosphate + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
(11Z,14Z)-eicosadienoateReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
3. (11Z,14Z)-eicosadienoyl-CoA hydrolase
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
(17Z)-hexacosenoateReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (ximenic acid)
3. Hexacosenoyl-CoA hydrolase
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 6 morecytosol
(7Z,10Z,13Z,16Z)-docosatetraenoateReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (adrenic acid)
3. (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA hydrolase
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 6 morecytosolOne of 2 routes
2,6,10,14-tetramethylpentadecanoateReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. fatty-acid-CoA ligase
3. peroxisomal acyl-CoA thioesterase
Catalysed by BAAT, ACOT6, SLC27A2, ACOT2cytosol, peroxisomeOne of 2 routes
a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA
Catalysed by LPCAT2, LPCAT1cytosolOne of 2 routes
a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by LPCAT4cytosol
1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. Octanoyl-CoA:L-carnitine O-octanoyltransferase
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octanoyl-CoA = 1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by BAAT, ACOT6, CROT, LPCAT4cytosol, mitochondrial matrix
1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 6 morecytosol
tetracosan-1-olReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lignocerate)
3. tetracosanoyl-CoA + 2 NADPH + 2 H(+) = tetracosan-1-ol + 2 NADP(+) + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
(2E,9Z)-hexadecadienoyl-CoAReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (palmitolate)
3. medium-chain acyl-CoA dehydrogenase (palmitoleoyl-CoA)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 10 morecytosol, mitochondrial matrixOne of 3 routes
trans-2-heptadecenoyl-CoAReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (margaric acid)
3. medium-chain acyl-CoA dehydrogenase (heptadecanoyl-CoA)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 10 morecytosol, mitochondrial matrixOne of 2 routes
(2E,9Z)-octadecadienoyl-CoAReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. Transport of octadecenoyl-CoA into Mitochondrial Matrix
3. medium-chain acyl-CoA dehydrogenase (oleoyl-CoA)
Catalysed by BAAT, ACOT6, CPT1A, CPT1C and 5 morecytosol, mitochondrial matrixOne of 2 routes
(2E,9Z,12Z)-octadecatrienoyl-CoAReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. (9Z,12Z)-octadecadienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,9Z,12Z)-octadecatrienoyl-CoA + reduced [electron-transfer flavoprotein]
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 9 morecytosol
(2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoAReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (DHA)
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + O2 = (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + H2O2
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
N-(9Z-octadecenoyl)-sphing-4-enineReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. acyl-CoA:sphingosine N-acyltransferase
3. N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
Catalysed by BAAT, ACOT6, ASAH1, ACER2 and 3 morecytosol, Golgi apparatus
9-cis-retinolReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. Palmitoyl-CoA:retinol O-acyltransferase
3. 11-cis-retinol = 9-cis-retinol
Catalysed by BAAT, ACOT6, DGAT1, LRAT and 4 morecytosol
N-hexadecanoyl-sphinganine-1-phosphocholineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by LPGAT1, SGMS1, SGMS2cytosol
N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by LPGAT1, SGMS1, SGMS2cytosol
an N-acyl-(4R)-4-hydroxysphinganine-phosphocholineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-(4R)-4-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by LPGAT1, SGMS1, SGMS2cytosol
N-hexadecanoyl-sphinganine-1-phosphoethanolamineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
3. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-sphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 2 morecytosol
an N-acylsphinganine-1-phosphoethanolamineReach from here →
1. acyl-CoA pool formation and breakdown
2. sphingosine N-acyltransferase (sphinganine)
3. an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by CERS1, CERS6, CERS3, CERS5 and 4 morecytosolOne of 2 routes
N-hexadecanoyl-(4R)-hydroxysphinganine-1-phosphoethanolamineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
3. N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-(4R)-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 2 morecytosol
an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoethanolamineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
3. an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 2 morecytosol
tricosanoateReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (tricosanoic acid)
3. Tricosanoyl-CoA hydrolase
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 6 morecytosol
thio-Mo-molybdopterinReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. N-acetylglutamate synthase (N-acetyl-L-cysteine)
3. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
Catalysed by BAAT, ACOT6, NAGS, MOCOScytosol, mitochondrial matrix
cholesteryl octadecanoateReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. Acyl-CoA:cholesterol O-acyltransferase
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol, endoplasmic reticulumOne of 6 routes
N-octadecanoylhexadecasphinganineReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. hexadecasphinganine + octadecanoyl-CoA = N-octadecanoylhexadecasphinganine + CoA + H(+)
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphateReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (DHA)
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol
1-hexadecanoyl-2-eicosanoyl-sn-glycero-3-phosphocholineReach from here →
1. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-eicosanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 7 morecytosol