N-hexadecanoylsphinganine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

308 compounds within 3 steps: 5 in 1, 43 in 2, 260 in 3

Three steps

tetracosanoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (lignocerate)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 10 routes
docosanoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (behenic acid)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 9 routes
a 2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
3. a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)
Catalysed by SGMS1, SGMS2, SELENOI, CEPT1 and 1 moreOne of 2 routes
an N-acylsphinganine-1-phosphocholineReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
3. an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acylsphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by SGMS1, SGMS2One of 2 routes
3-oxooctadecanoyl-CoAReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. hexadecanoyl-CoA + malonyl-CoA + H(+) = 3-oxooctadecanoyl-CoA + CO2 + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 11 more
(2E)-octadecenoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. Carnitine O-Palmitoyltransferase
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 6 morecytosolOne of 3 routes
(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (stearidonic acid)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 8 routes
(8Z,11Z,14Z)-eicosatrienoateReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. 1,2-diacyl-sn-glycerol acylhydrolase
3. (10Z)-heptadecenoic acid formation
Catalysed by SGMS1, SGMS2, LPLextracellular spaceOne of 12 routes
1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-O-hexadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 9 more
1,2-dihexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 11 more
1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 9 more
1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 9 more
1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 9 more
1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 9 more
1,2-dihexadecanoyl-sn-glycero-3-phosphateReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-hexadecanoyl-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 9 more
N-(hexadecanoyl)-sphing-4-enine-1-phosphateReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. N-hexadecanoylsphing-4-enine + H2O = sphing-4-enine + hexadecanoate
3. N-hexadecanoylsphing-4-enine + ATP = N-(hexadecanoyl)-sphing-4-enine-1-phosphate + ADP + H(+)
Catalysed by ASAH2, NAAA, ASAH1, ACER2 and 1 more
1,2-dihexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 11 more
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 9 more
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 9 more
an N-acylsphing-4-enine 1-phosphoethanolamineReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
3. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphing-4-enine 1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by SGMS1, SGMS2, SAMD8One of 2 routes
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (EPA)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 9 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (DPA)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 6 routes
(9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (linolenate)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 7 routes
(13Z)-docosenoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (cis-erucic acid)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 6 routes
(11Z)-eicosenoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 7 routes
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 5 routes
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 4 routes
2-hydroxyhexadecanoyl-CoAReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. hexadecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyhexadecanoyl-CoA + succinate + CO2
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 9 more
(15Z)-tetracosenoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (nervonic acid)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 6 routes
(17Z)-hexacosenoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (ximenic acid)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 4 routes
(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 5 routes
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 5 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 7 routes
heptadecanoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 6 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 5 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 5 routes
(6Z)-hexadecenoyl-CoAReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (6Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 9 more
N-acetylcysteamineReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. S-hexadecanoyl-N-acetylcysteamine + H2O = N-acetylcysteamine + hexadecanoate + H(+)
3. S-hexadecanoyl-N-acetylcysteamine + H2O = N-acetylcysteamine + hexadecanoate + H(+)
Catalysed by ASAH2, PPT1, PPT2
1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphateReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 15 more
1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 10 more
1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphoserineReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphoserine + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 9 more
1-dodecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-dodecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-dodecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 10 more
1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-octadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 10 more
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 9 more
1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1-tetradecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 10 more
nonadecanoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 11 morecytosolOne of 6 routes
(11Z)-octadecenoyl-CoAReach from here →
1. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
2. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
3. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by SGMS1, SGMS2, DGAT1, MOGAT2 and 6 morecytosolOne of 3 routes
1'-[1-acyl-2-hexadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA = 1'-[1-acyl-2-hexadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 9 more
1-acyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. a 1-acyl-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 9 more
1-acyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O
2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
3. a 1-acyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ASAH2, SLC27A2, ACSL4, ACSL3 and 10 more