(2E)-butenoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

139 compounds within 3 steps: 2 in 1, 9 in 2, 128 in 3

Three steps

(2E)-octadecenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. Carnitine O-Palmitoyltransferase
Catalysed by GCDH, CPT1A, CPT1C, CPT1BcytosolOne of 3 routes
(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (stearidonic acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 8 routes
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (EPA)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 9 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (DPA)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 6 routes
(9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (linolenate)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 7 routes
(13Z)-docosenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (cis-erucic acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 6 routes
(11Z)-eicosenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 7 routes
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 5 routes
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 4 routes
(15Z)-tetracosenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (nervonic acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 6 routes
(17Z)-hexacosenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (ximenic acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 4 routes
(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 5 routes
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 5 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 7 routes
heptadecanoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 6 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 5 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 5 routes
nonadecanoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 6 routes
(11Z)-octadecenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by GCDH, CPT1A, CPT1C, CPT1BcytosolOne of 3 routes
dodecanedioyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. Activation of dodecanedioic acid
Catalysed by GCDH, CPT1A, CPT1C, CPT1BcytosolOne of 4 routes
decanedioyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. Production of Sebacoylcarnitine
Catalysed by GCDH, CPT1A, CPT1C, CPT1BcytosolOne of 4 routes
octanedioyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. Production of Suberylcarnitine
Catalysed by GCDH, CPT1A, CPT1C, CPT1BcytosolOne of 4 routes
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 7 routes
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 5 routes
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by GCDH, CPT1A, CPT1C, CPT1Bcytosol
(13Z)-eicosenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 5 routes
4,8-dimethylnonanoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 2 morecytosol, peroxisomeOne of 3 routes
tetradecanedioyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 4 morecytosol, peroxisome
hexadecanedioyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. Production of Hexadecanedioylcarnitine
Catalysed by GCDH, CPT1A, CPT1C, CPT1BcytosolOne of 2 routes
pristanoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. fatty-acid-CoA ligase
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 1 morecytosolOne of 2 routes
undecanoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 6 morecytosolOne of 3 routes
17beta-estradiol 17-O-(beta-D-glucuronate)Reach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. glutaryl-CoA + H2O = glutarate + CoA + H(+)
3. 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + glutarate(in) = 17beta-estradiol 17-O-(beta-D-glucuronate)(in) + glutarate(out)
Catalysed by GCDH, ACOT8, ACOT4, SLC22A24inner side of the membrane, outer side of the membraneOne of 2 routes
(5Z)-tetradecenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 8 routes
(3E)-decenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 4 morecytosol, mitochondrial matrix
O-3-oxobutanoyl-(R)-carnitineReach from here →
1. (S)-3-hydroxybutanoyl-CoA hydro-lyase
2. (3S)-3-hydroxybutanoyl-CoA + NAD(+) = acetoacetyl-CoA + NADH + H(+)
3. acetoacetyl-CoA + (R)-carnitine = O-3-oxobutanoyl-(R)-carnitine + CoA
Catalysed by ECHS1, HADH, HSD17B10, CRATmitochondrial matrix
(2R,6)-dimethylheptanoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 3 morecytosol, mitochondrial matrix
(7Z)-hexadecenoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 8 routes
tricosanoyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. Production of Glutaryl Carnitine
3. long-chain-fatty-acid-CoA ligase (tricosanoic acid)
Catalysed by GCDH, CPT1A, CPT1C, CPT1B and 8 morecytosolOne of 4 routes
a 3-oxoacyl-CoAReach from here →
1. glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
2. glutarate + succinyl-CoA = glutaryl-CoA + succinate
3. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
Catalysed by GCDH, SUGCT, OXCT1, OXCT2