a 1,2-diacyl-sn-glycerol

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

837 compounds within 3 steps: 18 in 1, 200 in 2, 619 in 3

Two steps

tetracosanoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (lignocerate)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 10 routes
docosanoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (behenic acid)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 9 routes
a 2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
2. a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)
Catalysed by SELENOI, CEPT1, DDHD1One of 2 routes
an N-acylsphinganine-1-phosphocholineReach from here →
1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acylsphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by SGMS1, SGMS2One of 2 routes
(2E)-octadecenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. Carnitine O-Palmitoyltransferase
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 4 morecytosolOne of 3 routes
(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (stearidonic acid)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 8 routes
(8Z,11Z,14Z)-eicosatrienoateReach from here →
1. 1,2-diacyl-sn-glycerol acylhydrolase
2. (10Z)-heptadecenoic acid formation
Catalysed by LPLextracellular spaceOne of 12 routes
an N-acylsphing-4-enine 1-phosphoethanolamineReach from here →
1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphing-4-enine 1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by SGMS1, SGMS2, SAMD8One of 2 routes
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (EPA)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 9 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (DPA)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 6 routes
(9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (linolenate)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 7 routes
(13Z)-docosenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (cis-erucic acid)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 6 routes
(11Z)-eicosenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 7 routes
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 5 routes
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 4 routes
(15Z)-tetracosenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (nervonic acid)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 6 routes
(17Z)-hexacosenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (ximenic acid)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 4 routes
(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 5 routes
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 5 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 7 routes
heptadecanoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 6 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 5 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 5 routes
nonadecanoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 6 routes
(11Z)-octadecenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 4 morecytosolOne of 3 routes
a 2,3-diacyl-sn-glycerolReach from here →
1. an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA
2. a triacyl-sn-glycerol + H2O = a 2,3-diacyl-sn-glycerol + a fatty acid + H(+)
Catalysed by DGAT1, MOGAT2, AWAT2, MOGAT3 and 3 moreOne of 2 routes
1-O-alkyl-3-acylglycerolReach from here →
1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. 1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-alkyl-3-acylglycerol + a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by SGMS1, SGMS2, PLA2G15One of 2 routes
dodecanedioyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. Activation of dodecanedioic acid
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 1 morecytosolOne of 4 routes
decanedioyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. Production of Sebacoylcarnitine
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 4 morecytosolOne of 4 routes
octanedioyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. Production of Suberylcarnitine
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 4 morecytosolOne of 4 routes
hexanedioyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. Activation of adipic acid for Formation of Adipoyl Carnitine
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 1 morecytosolOne of 4 routes
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 7 routes
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 5 routes
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 4 morecytosol
(13Z)-eicosenoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 9 morecytosolOne of 5 routes
1-O-alkyl-2,3-diacyl-sn-glycerolReach from here →
1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. 1-O-alkyl-2-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-alkyl-2,3-diacyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine
Catalysed by SGMS1, SGMS2, PLA2G15One of 2 routes
4,8-dimethylnonanoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 3 morecytosol, peroxisomeOne of 3 routes
tetradecanedioyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 5 morecytosol, peroxisome
hexadecanedioyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. Production of Hexadecanedioylcarnitine
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 4 morecytosolOne of 2 routes
(11Z,14Z)-eicosadienoateReach from here →
1. 1,2-diacyl-sn-glycerol acylhydrolase
2. (10Z)-heptadecenoic acid formation
Catalysed by LPLextracellular spaceOne of 12 routes
(17Z)-hexacosenoateReach from here →
1. 1,2-diacyl-sn-glycerol acylhydrolase
2. (10Z)-heptadecenoic acid formation
Catalysed by LPLextracellular spaceOne of 12 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoateReach from here →
1. 1,2-diacyl-sn-glycerol acylhydrolase
2. (10Z)-heptadecenoic acid formation
Catalysed by LPLextracellular spaceOne of 12 routes
(7Z,10Z,13Z,16Z)-docosatetraenoateReach from here →
1. 1,2-diacyl-sn-glycerol acylhydrolase
2. (10Z)-heptadecenoic acid formation
Catalysed by LPLextracellular spaceOne of 12 routes
pristanoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. fatty-acid-CoA ligase
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 2 morecytosolOne of 2 routes
a 1,3-diacyl-sn-glycerolReach from here →
1. an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA
2. a triacyl-sn-glycerol + H2O = a 1,3-diacyl-sn-glycerol + a fatty acid + H(+)
Catalysed by DGAT1, MOGAT2, AWAT2, MOGAT3 and 3 moreOne of 2 routes
undecanoyl-CoAReach from here →
1. acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 7 morecytosolOne of 3 routes
a fatty acyl-CoAReach from here →
1. a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)
2. a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate
Catalysed by DAGLB, ABHD11, DAGLA, ACSL3
(5Z,8Z,11Z)-eicosatrienoateReach from here →
1. 1,2-diacyl-sn-glycerol acylhydrolase
2. (10Z)-heptadecenoic acid formation
Catalysed by LPLextracellular spaceOne of 12 routes
N-hexadecanoyl-sphinganine-1-phosphocholineReach from here →
1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by SGMS1, SGMS2One of 2 routes
N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholineReach from here →
1. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol
2. N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by SGMS1, SGMS2One of 2 routes