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Proteins/UNIPROT:O43567
E3 ubiquitin-protein ligase that regulates cell proliferation. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA. Also involved in protein trafficking and localization..
Function from UniProtKB (O43567), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
14 statements
14 statements · 2 reference databases · Subject: RNF13 · Sources: gene ontology, Hetionet
1 reaction
2 names
Resolves to: RNF13
Reaction pageLeft to rightBalance undeterminableEC 2.3.2.23, 2.3.2.27, 6.2.1.45cytosol
Human-GEM MAR09491CC BY 4.0Reference data