Pathway
RND2 GTPase cycle
RND2 (RHON) is an atypical RHO GTPase and the least studied member of the RND subfamily. RND2 is constitutively bound to GTP and lacks GTPase activity. No guanine nucleotide exchange factors (GEFs), GTPase activator proteins (GAPs) or guanine nucleotide dissociation inhibitors (GDIs) act on RND2. RND2 is predominantly expressed in brain, testis and liver. RND2 regulates neurite outgrowth and branching and migration of newborn neurons within the embryonic cerebral cortex.
REACT:R-HSA-9696270Reactome
What the reference databases state
Statements
43 statements
43 statements · 1 reference database · Subject: RND2 GTPase cycle · Sources: Reactome
- ALDH3A2 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- ANKRD26 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- ARHGAP1 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- ARHGAP35 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- ARHGAP5 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- BLTP3B participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- CAV1 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- CKAP4 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- DEPDC1B participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- DLG5 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- DSG1 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- DST participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
Show the remaining 31
- EPHA2 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- FNBP1 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- FRS2 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- FRS3 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- GOLGA3 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- KCTD13 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- KIDINS220 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- KIF14 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- KTN1 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- LEMD3 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- LRRC1 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- MUC13 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- NISCH participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- NUDC participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- PIK3R1 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- PIK3R2 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- PKP4 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- PLXND1 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- PRAG1 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- PTPN13 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- RBMX participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- RND2 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- SACK1B participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- SCRIB participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- TFRC participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- TNFAIP1 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- TXNL1 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- UBXN11 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- VANGL1 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- VANGL2 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only
- WDR6 participates in RND2 GTPase cycleProteinReactome R-HSA-9696270Inferred only