(7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

128 compounds within 3 steps: 1 in 1, 35 in 2, 92 in 3

Three steps

1-hexadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine
Catalysed by ACAA1, LPCAT3, MBOAT7, PLA2G15One of 2 routes
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholineReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine
Catalysed by ACAA1, LPCAT3, MBOAT7, PLA2G15One of 5 routes
1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enineReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by ACAA1, LPCAT3, MBOAT7, PLA2G15One of 3 routes
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + CoA
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by ACAA1, LPCAT3, PLA2G15One of 3 routes
20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. arachidonic acid:oxygen 1-oxidoreductase
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 29 morecytosolOne of 3 routes
11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 3 more
19-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 7 more
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-L-serineReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + H2O = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-L-serine + hexadecanoate + H(+)
Catalysed by ACAA1, LPCAT3, PLA1A
2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
3. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + octadecanoate + H(+)
Catalysed by ACAA1, AGPAT3, DDHD1
1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z- eicosatetraenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. 1-octadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-(1Z-octadecenyl)-sn-glycero-3-phosphoethanolamine + 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine = 1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z- eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + 1-octadecanoyl-sn-glycero-3-phosphocholine
Catalysed by ACAA1, LPCAT3, TMEM164
(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + A + H2O
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 3 moreOne of 2 routes
(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + A + H2O
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 3 moreOne of 2 routes
hexadecanoateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + hexadecanoate + H(+)
Catalysed by ACAA1, LPCAT3, MBOAT7, PLA2G4B and 5 moreOne of 3 routes
(15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 3 more
11R-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. Arachidonate: oxygen 11-oxidoreductase
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 3 morecytosolOne of 2 routes
prostaglandin G2Reach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. Arachidonate:oxygen oxidoreductase
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 4 moreendoplasmic reticulumOne of 2 routes
(12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 3 more
14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. unspecific monooxygenase (arachidonate)
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 29 morecytosolOne of 4 routes
8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. unspecific monooxygenase (arachidonate)
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 28 morecytosolOne of 3 routes
1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoserineReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoserine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphoserine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 3 more
1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 3 more
1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 3 more
N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)
Catalysed by ACAA1, LPCAT3, MBOAT7, PLAAT5
1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-cytidine-5'-diphosphateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
3. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CTP + H(+) = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate
Catalysed by ACAA1, AGPAT3, CDS2, CDS1
1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-cytidine-5'-diphosphateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. 1-hexadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CTP + H(+) = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate
Catalysed by ACAA1, AGPAT2, AGPAT3, CDS2 and 1 more
(18R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (18R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 3 more
15-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 15-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 3 more
5-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + acetyl-CoA
2. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 5-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate
Catalysed by ACAA1, ACOT8, THEM4, THEM5 and 3 more