sn-glycero-3-phospho-1D-myo-inositol

Three steps

• hexacosanoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (cerotic acid)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 5 routes

• a 2-acyl-sn-glycero-3-phospho-D-myo-inositolReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)
  3. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + a fatty acid + H(+)

  Catalysed by GDE1, CDIPT, DDHD1cytosol

• tetracosanoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (lignocerate)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 10 routes

• docosanoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (behenic acid)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 9 routes

• (2E)-octadecenoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. Carnitine O-Palmitoyltransferase

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 4 morecytosolOne of 3 routes

• (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (stearidonic acid)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 8 routes

• D-ribulose 1-phosphateReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. sn-Glycerol-3-phosphate:(acceptor) 2-oxidoreductase
  3. L-xylulose 1-phosphate glycolaldehyde-lyase (glycerone-phosphate-forming)

  Catalysed by GDE1, GPD2, ALDOA, ALDOB and 1 morecytosol, mitochondrial matrix

• 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
  1. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + (9Z)-octadecenoate + H(+)
  2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + (9Z)-octadecenoate + H(+)
  3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)

  Catalysed by ABHD12

• 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
  1. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + (9Z)-octadecenoate + H(+)
  2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + (9Z)-octadecenoate + H(+)
  3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + (9Z)-octadecenoate + H(+)

  Catalysed by ABHD12, ABHD16A

• 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphateReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
  3. 1-hexadecanoyl-sn-glycero-3-phosphate + octadecanoyl-CoA = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 2 morecytosol

• 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphateReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
  3. 1-hexadecanoyl-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 2 morecytosol

• 1,2-dihexadecanoyl-sn-glycero-3-phosphateReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
  3. 1-hexadecanoyl-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 2 morecytosol

• 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphateReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
  3. 1-hexadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 3 morecytosol

• (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (EPA)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 9 routes

• (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (DPA)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 6 routes

• 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphateReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
  3. 1-hexadecanoyl-sn-glycero-3-phosphate + (9Z)-hexadecenoyl-CoA = 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 2 morecytosol

• (9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (linolenate)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 7 routes

• (13Z)-docosenoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (cis-erucic acid)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 6 routes

• (11Z)-eicosenoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 7 routes

• (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 5 routes

• (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 4 routes

• (15Z)-tetracosenoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (nervonic acid)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 6 routes

• (17Z)-hexacosenoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (ximenic acid)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 4 routes

• (8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 5 routes

• (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 5 routes

• (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (DHA)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 7 routes

• heptadecanoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (margaric acid)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 6 routes

• (9Z)-heptadecenoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 5 routes

• (11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 5 routes

• 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate + H(+)
  2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
  3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT4, GPAM and 9 more

• 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (linoleoyl-CoA)
  3. 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 2 morecytosol

• 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphateReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate + H(+)
  2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
  3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT4, GPAM and 6 more

• 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphateReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate + H(+)
  2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
  3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + octadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT4, GPAM and 5 more

• 1-(9Z)-octadecenoyl-2-heptadecanoyl-sn-glycero-3-phosphateReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate + H(+)
  2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
  3. heptadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-heptadecanoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT4, GPAM and 5 more

• 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
  3. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 5 morecytosol

• 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphateReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate + H(+)
  2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
  3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT4, GPAM and 5 moreOne of 2 routes

• 1-(9Z)-octadecenoyl-2-pentadecanoyl-sn-glycero-3-phosphateReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate + H(+)
  2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
  3. pentadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-pentadecanoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT4, GPAM and 5 more

• 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphateReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate + H(+)
  2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
  3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT4, GPAM and 4 more

• 1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (myristoyl-CoA)
  3. 1-tetradecanoyl-sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 3 morecytosol

• 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphateReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate + H(+)
  2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
  3. (9Z)-hexadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT4, GPAM and 1 more

• a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate + H(+)
  2. sn-glycerol 3-phosphate + an acyl-CoA = a 1-acyl-sn-glycero-3-phosphate + CoA
  3. a 1-acyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 2 more

• 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphateReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate + H(+)
  2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
  3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT4, GPAM and 6 more

• 1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphateReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate + H(+)
  2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
  3. eicosanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT4, GPAM and 1 more

• 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (arachidonyl-CoA)
  3. 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 3 morecytosol

• 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = 1D-myo-inositol 1-phosphate + glycerol + H(+)
  2. 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine
  3. 1-octadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA

  Catalysed by GDPD2, PLA2G4A, LPCAT3

• 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = 1D-myo-inositol 1-phosphate + glycerol + H(+)
  2. 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine
  3. 1-octadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA

  Catalysed by GDPD2, PLA2G4A, LPCAT3, LPCAT1

• 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = 1D-myo-inositol 1-phosphate + glycerol + H(+)
  2. 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine
  3. 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA

  Catalysed by GDPD2, PLA2G4A, MBOAT2

• 1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphateReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate + H(+)
  2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
  3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + dodecanoyl-CoA = 1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT4, GPAM and 1 more

• 1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphateReach from here →
  1. sn-glycero-3-phospho-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate + H(+)
  2. sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
  3. nonadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphate + CoA

  Catalysed by GDE1, GPAT3, GPAT4, GPAM and 3 more

• nonadecanoyl-CoAReach from here →
  1. 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase
  2. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
  3. long-chain-fatty-acid-CoA ligase (nonadecylic acid)

  Catalysed by GDE1, GPAT3, GPAT2, GPAT4 and 9 morecytosolOne of 6 routes