1-O-acyl-sn-glycero-3-phosphocholine(1+)

Two steps

• 3-hydroxyisovaleryl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. (3-Hydroxyisovalerylcoa->3-Hydroxyisovalerylcarnitine)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 2 morecytosol

• an all-trans-retinyl esterReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. Lecithin Retinol Acyltransferase

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 1 morecytosolOne of 4 routes

• CHEBI:63544Reach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (adrenic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 7 routes

• hexacosanoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (cerotic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 5 routes

• tetracosanoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (lignocerate)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 10 routes

• docosanoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (behenic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 9 routes

• (2E)-octadecenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. Carnitine O-Palmitoyltransferase

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 3 morecytosolOne of 3 routes

• (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (stearidonic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 8 routes

• (8Z,11Z,14Z)-eicosatrienoateReach from here →
  1. 1-Acyl-sn-glycero-3-phosphocholine acylhydrolase
  2. (10Z)-heptadecenoic acid formation

  Catalysed by LYPLA1, LYPLA2, PLA2G4A, PLB1 and 6 morecytosol, extracellular spaceOne of 12 routes

• (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (EPA)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 9 routes

• (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (DPA)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 6 routes

• (9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (linolenate)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 7 routes

• (13Z)-docosenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (cis-erucic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 6 routes

• (11Z)-eicosenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 7 routes

• (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 5 routes

• (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 4 routes

• (15Z)-tetracosenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (nervonic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 6 routes

• (17Z)-hexacosenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (ximenic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 4 routes

• (8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 5 routes

• (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 5 routes

• (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (DHA)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 7 routes

• heptadecanoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (margaric acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 6 routes

• (9Z)-heptadecenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 5 routes

• (11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 5 routes

• nonadecanoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (nonadecylic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 6 routes

• (11Z)-octadecenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 3 morecytosolOne of 3 routes

• dodecanedioyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. Activation of dodecanedioic acid

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1cytosolOne of 4 routes

• decanedioyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. Production of Sebacoylcarnitine

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 3 morecytosolOne of 4 routes

• octanedioyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. Production of Suberylcarnitine

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 3 morecytosolOne of 4 routes

• hexanedioyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. Activation of adipic acid for Formation of Adipoyl Carnitine

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1cytosolOne of 4 routes

• (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 7 routes

• (11Z,14Z)-eicosadienoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 5 routes

• (R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. Production of 3-Hydroxyoctadecenoylcarnitinec

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 3 morecytosol

• (13Z)-eicosenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 5 routes

• 4,8-dimethylnonanoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 2 morecytosol, peroxisomeOne of 3 routes

• tetradecanedioyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 4 morecytosol, peroxisome

• hexadecanedioyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. Production of Hexadecanedioylcarnitine

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 3 morecytosolOne of 2 routes

• (11Z,14Z)-eicosadienoateReach from here →
  1. 1-Acyl-sn-glycero-3-phosphocholine acylhydrolase
  2. (10Z)-heptadecenoic acid formation

  Catalysed by LYPLA1, LYPLA2, PLA2G4A, PLB1 and 6 morecytosol, extracellular spaceOne of 12 routes

• (17Z)-hexacosenoateReach from here →
  1. 1-Acyl-sn-glycero-3-phosphocholine acylhydrolase
  2. (10Z)-heptadecenoic acid formation

  Catalysed by LYPLA1, LYPLA2, PLA2G4A, PLB1 and 6 morecytosol, extracellular spaceOne of 12 routes

• (7Z,10Z,13Z,16Z,19Z)-docosapentaenoateReach from here →
  1. 1-Acyl-sn-glycero-3-phosphocholine acylhydrolase
  2. (10Z)-heptadecenoic acid formation

  Catalysed by LYPLA1, LYPLA2, PLA2G4A, PLB1 and 6 morecytosol, extracellular spaceOne of 12 routes

• (7Z,10Z,13Z,16Z)-docosatetraenoateReach from here →
  1. 1-Acyl-sn-glycero-3-phosphocholine acylhydrolase
  2. (10Z)-heptadecenoic acid formation

  Catalysed by LYPLA1, LYPLA2, PLA2G4A, PLB1 and 6 morecytosol, extracellular spaceOne of 12 routes

• pristanoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. fatty-acid-CoA ligase

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 1 morecytosolOne of 2 routes

• a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholineReach from here →
  1. 1-Acyl-sn-glycero-3-phosphocholine acylhydrolase
  2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O = a 2,3-saturated aldehyde + sn-glycerol 3-phosphocholine

  Catalysed by LYPLA1, LYPLA2, PLA2G4A, PLB1 and 8 morecytosol

• undecanoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. medium-chain acyl-CoA ligase (undecylic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 6 morecytosolOne of 3 routes

• (5Z,8Z,11Z)-eicosatrienoateReach from here →
  1. 1-Acyl-sn-glycero-3-phosphocholine acylhydrolase
  2. (10Z)-heptadecenoic acid formation

  Catalysed by LYPLA1, LYPLA2, PLA2G4A, PLB1 and 6 morecytosol, extracellular spaceOne of 12 routes

• tricosanoateReach from here →
  1. 1-Acyl-sn-glycero-3-phosphocholine acylhydrolase
  2. (10Z)-heptadecenoic acid formation

  Catalysed by LYPLA1, LYPLA2, PLA2G4A, PLB1 and 6 morecytosol, extracellular spaceOne of 12 routes

• (5Z)-tetradecenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (physeteric acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 8 routes

• (3E)-decenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 4 morecytosol, mitochondrial matrix

• (2R,6)-dimethylheptanoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 3 morecytosol, mitochondrial matrix

• (7Z)-hexadecenoyl-CoAReach from here →
  1. Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
  2. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)

  Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 8 morecytosolOne of 8 routes